{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T10:55:41Z","timestamp":1792580141085,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T00:00:00Z","timestamp":1539561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction:<\/jats:italic> Many prognostic factors have been studied in carpal tunnel decompression, but most studies consider only a subset of variables. <jats:italic>Methods:<\/jats:italic> Three thousand three hundred thirty\u2010two operations were used to develop prognostic models, and 885 operations were used for validation. Outcome recorded on a Likert scale was dichotomized into success or failure. Modeling was performed with both logistic regression and artificial neural networks using 87 candidate variables. <jats:italic>Results:<\/jats:italic> Both approaches produced predictive multivariate models for outcome with areas under a receiver operating characteristic curve of 0.7 in the validation data set. Patients with moderately severe nerve conduction abnormalities, night waking, a family history of carpal tunnel syndrome, a good response to corticosteroid injection, and women have better outcomes. Greater functional impairment, diabetes, hypertension, and surgery on the dominant hand are associated with poorer outcomes. <jats:italic>Discussion:<\/jats:italic> A multivariate model partially predicts the outcome of carpal tunnel surgery, aids decision making, and helps to manage patient expectations. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>58<\/jats:bold>:784\u2013789, 2018<\/jats:p>","DOI":"10.1002\/mus.26297","type":"journal-article","created":{"date-parts":[[2018,7,7]],"date-time":"2018-07-07T07:36:39Z","timestamp":1530948999000},"page":"784-789","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["A prognostic model for the patient\u2010reported outcome of surgical treatment of carpal tunnel syndrome"],"prefix":"10.1002","volume":"58","author":[{"given":"Angela","family":"Bowman","sequence":"first","affiliation":[{"name":"Department of Health Informatics Norfolk and Suffolk NHS Foundation Trust  Ipswich Suffolk United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Rudolfer","sequence":"additional","affiliation":[{"name":"Centre for Biostatistics, School of Health Sciences, Division of Population Health, Health Services Research &amp; Primary Care University of Manchester  Manchester United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Weller","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Pharmacology and Postgraduate Medicine, School of Life and Medical Sciences University of Hertfordshire  Hatfield United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5591-6022","authenticated-orcid":false,"given":"Jeremy D. P.","family":"Bland","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurophysiology East Kent Hospitals University NHS Foundation Trust, Ethelbert Road  Canterbury Kent United Kingdom CT1 3NG"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20802"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.JHSB.2005.09.022"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199311000-00002"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.22158"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecolmodel.2004.03.013"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","unstructured":"WatchmakerJD WatchmakerGP.Independent variables affecting outcome of carpal tunnel surgery. 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