{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:40:43Z","timestamp":1747150843461,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,10,17]],"date-time":"2018-10-17T00:00:00Z","timestamp":1539734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction<\/jats:italic>: A rare association of proton pump inhibitor (PPI) use with the development of inflammatory myopathies (IM) has been reported, but, unlike with statin medications, there is limited data supporting or refuting this observation. <jats:italic>Methods<\/jats:italic>: A case\u2010control study was conducted on patients with IM. Clinical information, medications, and demographics were recorded. Controls were matched 3:1 for age and gender. <jats:italic>Results<\/jats:italic>: Two hundred twenty\u2010one cases of IM were identified. No association of PPI use with IM was observed when compared with controls (odds ratio 1.04 [95% confidence interval 0.68\u20131.58]) and similar results were observed after adjusting for diabetes, cardiovascular disease, and statin exposure (adjusted odds ratio 1.084 [95% confidence interval 0.69\u20131.70]). There was no association of any histologic subtype of IM with PPI exposure. <jats:italic>Discussion<\/jats:italic>: Our findings do not support an association of PPI exposure with IM. Co\u2010prescription of PPI with other medications was not considered and could be further investigated with larger cohorts. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>58<\/jats:bold>:855\u2013857, 2018<\/jats:p>","DOI":"10.1002\/mus.26336","type":"journal-article","created":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T11:55:11Z","timestamp":1536321311000},"page":"855-857","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Proton pump inhibitors are not associated with inflammatory myopathies: A case control study"],"prefix":"10.1002","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1122-3384","authenticated-orcid":false,"given":"Thomas","family":"Khoo","sequence":"first","affiliation":[{"name":"Central Adelaide Local Health Network  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gillian E.","family":"Caughey","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Discipline of Pharmacology, Adelaide Medical School University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Hill","sequence":"additional","affiliation":[{"name":"Rheumatology Unit, The Queen Elizabeth Hospital  Adelaide South Australia"},{"name":"Rheumatology Unit The Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Discipline of Medicine, School of Medicine University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vidya","family":"Limaye","sequence":"additional","affiliation":[{"name":"Rheumatology Unit The Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Discipline of Medicine, School of Medicine University of Adelaide  Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2015.1013981"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1969"},{"key":"e_1_2_7_4_1","unstructured":"Australian Government Department of Health.Pharmaceutical benefits scheme: expenditure and prescriptions twelve months to 30 June 2015. Australian Government Department of Health Canberra Australia;2016."},{"key":"e_1_2_7_5_1","first-page":"701","article-title":"Gastro\u2010oesophageal reflux disease (GORD) in Australian general practice patients","volume":"44","author":"Miller G","year":"2015","journal-title":"Austral Fam Physician"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOL.0000000000000399"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-006-0131-1"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/009286150804200501"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1060028016665641"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X16650156"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118635469.ch33"},{"key":"e_1_2_7_12_1","unstructured":"North West Adelaide Health Study: Stage 2 Key Findings: Department of Health; Adelaide; May 2007."},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1756-185X.2010.01470.x"},{"key":"e_1_2_7_14_1","first-page":"747","volume":"48","author":"Rehman ZU","year":"2016","journal-title":"A novel ultrastructural finding in statin\u2010exposed patients with inflammatory myositis. 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