{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T14:19:26Z","timestamp":1761401966521},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T00:00:00Z","timestamp":1539561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Motor Neuron Disease Research Institute of Australia"},{"name":"National Health and Medical Research Council of Australia","award":["510233","1024915","1055778"],"award-info":[{"award-number":["510233","1024915","1055778"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n<jats:italic>Introduction<\/jats:italic>: Reproducibility of the multiple point stimulation motor unit number estimation (MPS\u2010MUNE) technique was compared with the recently developed motor unit number index (MUNIX) technique. <jats:italic>Methods<\/jats:italic>: MPS\u2010MUNE and MUNIX were performed on 15 healthy subjects at 3 different time\u2010points by the same examiner. Reproducibility was analyzed using intraclass correlation coefficient (ICC) and coefficient of variation (CV). <jats:italic>Results<\/jats:italic>: ICC values for MUNIX and MPS\u2010MUNE were excellent across 3 tests (0.80 and 0.77, respectively), although CV values were significantly lower for MUNIX than MPS\u2010MUNE (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). In addition, test\u2010retest reproducibility was better for MUNIX, a finding largely attributable to poor reproducibility of the single motor unit action potential area. MUNIX (<jats:italic>R<\/jats:italic>\u2009=\u2009\u22120.48, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) and MPS\u2010MUNE (<jats:italic>R<\/jats:italic>\u2009=\u2009\u22120.53, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) were significantly correlated with age. <jats:italic>Discussion<\/jats:italic>: MUNIX demonstrated better intrarater reproducibility and may be a more reliable neurophysiological biomarker than MPS\u2010MUNE. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>58<\/jats:bold>: 660\u2013664, 2018<\/jats:p>","DOI":"10.1002\/mus.26339","type":"journal-article","created":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T20:00:15Z","timestamp":1536436815000},"page":"660-664","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Reproducibility of motor unit number index and multiple point stimulation motor unit number estimation in controls"],"prefix":"10.1002","volume":"58","author":[{"given":"Mana","family":"Higashihara","sequence":"first","affiliation":[{"name":"Department of Neurology Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parvathi","family":"Menon","sequence":"additional","affiliation":[{"name":"Westmead Clinical School, Cnr. Hawkesbury and Darcy Road University of Sydney  New South Wales 2145 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"van den Bos","sequence":"additional","affiliation":[{"name":"Westmead Clinical School, Cnr. Hawkesbury and Darcy Road University of Sydney  New South Wales 2145 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nimeshan","family":"Geevasinga","sequence":"additional","affiliation":[{"name":"Westmead Clinical School, Cnr. Hawkesbury and Darcy Road University of Sydney  New South Wales 2145 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve","family":"Vucic","sequence":"additional","affiliation":[{"name":"Westmead Clinical School, Cnr. Hawkesbury and Darcy Road University of Sydney  New South Wales 2145 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,10,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.34.2.121"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.39.10.973"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880110503"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880160404"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-199511000-00005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880170807"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20031"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2004.834281"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24442"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24979"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21824"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.02.017"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2012.08.023"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2012.01.004"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2015.05.004"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2005.11.011"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2006.07.304"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.6.4.284"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.34.2.113"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.35.6.845"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.39.3.258"},{"key":"e_1_2_6_23_1","first-page":"957","article-title":"Statistical estimates of number of motor units in thenar and foot muscles in patients with amyotrophic lateral sclerosis or the residual of poliomyelitis","volume":"11","author":"Daube J","year":"1988","journal-title":"Muscle Nerve"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410280404"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880141114"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4598(200010)23:10<1525::AID-MUS8>3.0.CO;2-E"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880181211"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2017.03.045"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21765"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.26339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.26339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T04:41:04Z","timestamp":1694320864000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.26339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,15]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1002\/mus.26339"],"URL":"https:\/\/doi.org\/10.1002\/mus.26339","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,15]]},"assertion":[{"value":"2018-09-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}