{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T23:20:28Z","timestamp":1767136828157,"version":"build-2238731810"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T00:00:00Z","timestamp":1559865600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007155","name":"Medical Research Council Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007155","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The Inclusion Body Myositis Functional Rating Scale (IBMRFS) is a 10\u2010item clinician\u2010rated ordinal scale developed for people with inclusion body myositis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Single observations of the IBMFRS were collected from 132 patients. After Rasch analysis, modifications were made to the scale to optimize fit to the Rasch model while maintaining clinical validity and utility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The original IBMFRS did not fit the assumptions of the Rasch model because of multidimensionality of the scale. Items assessed local dependence, disordered step thresholds, and differential item functioning. Deconstructing the scale into upper limb (IBMFRS\u2010UL) and lower limb (IBMFRS\u2010LL) scales improved fit to the Rasch model. A 9\u2010item scale with the swallowing item removed (IBMFRS\u20109) remained multidimensional but demonstrated the ability to discriminate patients along the severity continuum. IBMFRS\u2010UL, IBMFRS\u2010LL, and IBMFRS\u20109 scores were transformed to a 0\u2013100 scale for comparability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>\n                      This analysis has led to the development of 3 optimized versions of the IBMFRS.\n                      <jats:italic>Muscle Nerve<\/jats:italic>\n                      <jats:bold>60<\/jats:bold>\n                      : 161\u2013168, 2019\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.26521","type":"journal-article","created":{"date-parts":[[2019,5,20]],"date-time":"2019-05-20T11:53:41Z","timestamp":1558353221000},"page":"161-168","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Investigation of the psychometric properties of the inclusion body myositis functional rating scale with rasch analysis"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9344-0301","authenticated-orcid":false,"given":"Gita","family":"Ramdharry","sequence":"first","affiliation":[{"name":"Queen Square MRC Centre for Neuromuscular Diseases Institute of Neurology, University College London  8\u201011 Queen Square, London WC1N 3BG United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jasper","family":"Morrow","sequence":"additional","affiliation":[{"name":"Queen Square MRC Centre for Neuromuscular Diseases Institute of Neurology, University College London  8\u201011 Queen Square, London WC1N 3BG United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacie","family":"Hudgens","sequence":"additional","affiliation":[{"name":"Clinical Outcomes Solutions  Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iwona","family":"Skorupinska","sequence":"additional","affiliation":[{"name":"Queen Square MRC Centre for Neuromuscular Diseases Institute of Neurology, University College London  8\u201011 Queen Square, London WC1N 3BG United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"Gwathmey","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Virginia  Charlottesville Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Currence","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Division University of Kansas  Fairway Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Herbelin","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Division University of Kansas  Fairway Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Jawdat","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Division University of Kansas  Fairway Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamatha","family":"Pasnoor","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Division University of Kansas  Fairway Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"April","family":"Mcvey","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Division University of Kansas  Fairway Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Barohn","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Division University of Kansas  Fairway Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ted M.","family":"Burns","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Virginia  Charlottesville Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mazen M.","family":"Dimachkie","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Division University of Kansas  Fairway Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony A.","family":"Amato","sequence":"additional","affiliation":[{"name":"Neurology Department Brigham and Women's Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G.","family":"Hanna","sequence":"additional","affiliation":[{"name":"Queen Square MRC Centre for Neuromuscular Diseases Institute of Neurology, University College London  8\u201011 Queen Square, London WC1N 3BG United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro M.","family":"Machado","sequence":"additional","affiliation":[{"name":"Queen Square MRC Centre for Neuromuscular Diseases Institute of Neurology, University College London  8\u201011 Queen Square, London WC1N 3BG United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,6,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20958"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25079"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25080"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.22321"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2013.02.010"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-011-0657-6"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2014.04.009"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00242-2"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2012.05.004"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003337"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aad4583"},{"key":"e_1_2_7_13_1","unstructured":"BenvenisteO HogrelJ AnnoussamyN BachassonD RigoletA ServaisL et al. Rapamycin vs. placebo for the treatment of inclusion body myositis: improvement of the 6 min walking distance a functional scale the FVC and muscle quantitative MRI. In: ACR Meeting Abstracts; October 19\u201324 2018; Chicago. IL. Available athttps:\/\/acrabstracts.org\/abstract\/rapamycin\u2010vs\u2010placebo\u2010for\u2010the\u2010treatment\u2010of\u2010inclusion\u2010body\u2010myositis\u2010improvement\u2010of\u2010the\u20106\u2010min\u2010walking\u2010distance\u2010a\u2010functional\u2010scale\u2010the\u2010fvc\u2010and\u2010muscle\u2010quantitative\u2010mri\/. 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