{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T23:26:19Z","timestamp":1756682779685,"version":"3.40.5"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T00:00:00Z","timestamp":1562716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction<\/jats:italic>: Duchenne muscular dystrophy (DMD) is characterized by absence of the subsarcolemmal protein dystrophin, present in skeletal muscles and cardiomyocytes. We hypothesized that progressive respiratory and left ventricular (LV) insufficiencies in DMD could be parallel and interrelated phenomena. <jats:italic>Methods<\/jats:italic>: We conducted a retrospective chart review of 27 patients with DMD. Our primary objective was to compare the rates of decline between pulmonary function test (PFT) measures (forced expiratory volume in the first second, forced vital capacity, peak expiratory flow rate, maximal inspiratory\/expiratory pressure) and echocardiographic estimates of LV end\u2010diastolic volume and LV ejection fraction. <jats:italic>Results<\/jats:italic>: The rates of decline\/year of PFTs and LV estimates were not significantly different. Pulmonary function test measures of ventilatory efficiency and strength had strong intercorrelations. Pulmonary function tests and LV estimates had weak but statistically significant correlations. <jats:italic>Discussion<\/jats:italic>: A comparable rate of decline in PFTs and LV indices in DMD provides evidence for concurrently progressive deterioration in respiratory and LV functions. <jats:italic>Muscle Nerve<\/jats:italic>, 2019<\/jats:p>","DOI":"10.1002\/mus.26623","type":"journal-article","created":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T10:49:06Z","timestamp":1561718946000},"page":"286-291","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association between pulmonary function and left ventricular volume and function in duchenne muscular dystrophy"],"prefix":"10.1002","volume":"60","author":[{"given":"Arshjot","family":"Khokhar","sequence":"first","affiliation":[{"name":"Penn State College of Medicine  Hershey Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athira","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Cardiology University of California  San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Midya","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Bioinformatics Penn State College of Medicine  Hershey Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashutosh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Neurology Penn State College of Medicine  Hershey Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankita","family":"Sinharoy","sequence":"additional","affiliation":[{"name":"Department of Public Health Penn State College of Medicine  Hershey Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tariq Ali","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology Penn State College of Medicine  Hershey Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mutasim","family":"Abu\u2010Hasan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pulmonology University of Florida  Gainesville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7739-6320","authenticated-orcid":false,"given":"Pritish","family":"Mondal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Pulmonology Penn State College of Medicine  500 University Drive, PO Box 850, Hershey, Pennsylvania 17033 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/323646a0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.110.960740"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22847"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880040213"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23172"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.12.2103052"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(97)90001-0"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002060-200207000-00007"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2016.12.014"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(80)90385-X"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-009-9156-8"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0960-8966(96)00357-4"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(94)90672-6"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000126574.61061.25"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2006.10.018"},{"issue":"5","key":"e_1_2_7_17_1","article-title":"Diagnosis and management of diastolic dysfunction and heart failure","volume":"73","author":"Satpathy C","year":"2006","journal-title":"Am Fam Physician"},{"key":"e_1_2_7_18_1","first-page":"A5458","article-title":"Application of machine learning tools using lung function tests to predict the age of permanent wheelchair dependence in children with duchenne muscular dystrophy. 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