{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:14:13Z","timestamp":1772118853420,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T00:00:00Z","timestamp":1565222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Little is published on the prognosis of small fiber neuropathy (SFN).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of 101 patients with biopsy proven SFN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Study participants included 87 patients with length\u2010dependent SFN and 14 patients with non\u2013length\u2010dependent SFN. The average duration of symptoms was 3.2\u2009years prior to SFN diagnosis, and the average follow\u2010up duration after diagnosis was 6.2\u2009years. Neuropathic pain was present in 98% of patients and in 84.2% of patients at the final visit. The average total number of pain medications ever used was 4.4 per patient. Signs of autonomic dysfunction were initially present in 24.8% of patients, but improved in most. Large fiber involvement was seen in 11.9% of patients. Small fiber neuropathy affected employment and ambulation status in 5.3% and 6.3% of patients, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Small fiber neuropathy tends to be stable and rarely affects ambulation and employment status. Effective pain control remains a challenge.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.26648","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T10:38:39Z","timestamp":1564137519000},"page":"376-381","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Longitudinal follow\u2010up of biopsy\u2010proven small fiber neuropathy"],"prefix":"10.1002","volume":"60","author":[{"given":"Steven","family":"MacDonald","sequence":"first","affiliation":[{"name":"Department of Neurology Cleveland Clinic Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tara L.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Neurology Cleveland Clinic Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianbo","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Quantitative Health Sciences Learner Research Institute, Cleveland Clinic Foundation Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Polston","sequence":"additional","affiliation":[{"name":"Department of Neurology Cleveland Clinic Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuebing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology Cleveland Clinic Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.wco.0000177330.35147.70"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/practneurol-2013-000758"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25082"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn093"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000487717"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23971"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2016.0057"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.60.1.108"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23910"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.128801"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.56.5.540"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2013.01.008"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.02999.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182166ebe"},{"issue":"15","key":"e_1_2_8_16_1","doi-asserted-by":"crossref","first-page":"P1.435","DOI":"10.1212\/WNL.90.15_supplement.P1.435","article-title":"Patient Assisted Intervention for Neuropathy: Comparison of treatment in real life situations (PAIN\u2010CONTRoLS)","volume":"90","author":"Barohn R","year":"2018","journal-title":"Neurology."},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.091074"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.9.1701"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2009.00229.x"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-0224"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2012.05.007"}],"container-title":["Muscle &amp; 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