{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:21:05Z","timestamp":1791973265161,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T00:00:00Z","timestamp":1566259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study assesses the burden, distribution, and evolution of muscle inflammation and damage on MRI among subtypes of idiopathic inflammatory myopathy (IIM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Musculoskeletal MRIs performed in 66 patients with IIM and 10 patients with non\u2010IIM between 2009 and 2016 were retrospectively graded for muscle edema, fatty replacement (FR), and atrophy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Immune\u2010mediated necrotizing myopathy (IMNM) patients had severe and extensive lower limb muscle edema, FR, and atrophy. The pelvic muscles and adductors were significantly more affected than in patients with dermatomyositis and polymyositis. Inclusion body myositis (IBM) was characterized by marked anterior thigh involvement, which stabilized or progressed at follow\u2010up imaging. Atrophy and FR grades improved over time in some non\u2010IBM IIM patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Patients with IMNM and IBM have characteristic patterns of muscle MRI abnormalities that may allow them to be differentiated radiologically from other IIM subtypes. Muscle damage in non\u2010IBM IIM may be reversible.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.26660","type":"journal-article","created":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T15:14:01Z","timestamp":1565363641000},"page":"549-557","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Radiographic patterns of muscle involvement in the idiopathic inflammatory myopathies"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8528-4361","authenticated-orcid":false,"given":"Jessica A.","family":"Day","sequence":"first","affiliation":[{"name":"Rheumatology Department Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Bajic","sequence":"additional","affiliation":[{"name":"Radiology Department Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheridan","family":"Gentili","sequence":"additional","affiliation":[{"name":"Biostatistics and Epidemiology University of South Australia  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandy","family":"Patel","sequence":"additional","affiliation":[{"name":"Radiology Department Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidya","family":"Limaye","sequence":"additional","affiliation":[{"name":"Rheumatology Department Royal Adelaide Hospital  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24307"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197707000-00001"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.165.6.7484589"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e3282efdc66"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem088"},{"issue":"9","key":"e_1_2_8_7_1","first-page":"1897","article-title":"Magnetic resonance imaging criteria for distinguishing between inclusion body myositis and polymyositis","volume":"29","author":"Dion E","year":"2002","journal-title":"J Rheumatol."},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu422"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210198"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2004.06.027"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00868438"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ker001"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00242-2"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2016.11.001"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-012-2489-y"},{"issue":"5","key":"e_1_2_8_16_1","first-page":"689","article-title":"Novel assessment tools to evaluate clinical and laboratory responses in a subset of patients enrolled in the Rituximab in Myositis trial","volume":"32","author":"Rider LG","year":"2014","journal-title":"Clin Exp Rheumatol."},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.7113"},{"key":"e_1_2_8_18_1","first-page":"403","volume-title":"Practical Statistics for Medical Research","author":"Altman DG","year":"1991"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1178"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24661"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202915"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0181069"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27704"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200008)43:8<1866::AID-ANR24>3.0.CO;2-6"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24220"}],"container-title":["Muscle &amp; 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