{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T13:44:31Z","timestamp":1756993471368},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T00:00:00Z","timestamp":1567123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Several viruses have been described as causes of acquired inflammatory myopathies; however, the mechanisms by which they cause muscle disease are still unclear. The aim of this study was to describe the laboratory features of benign acute myositis in a small case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A detailed pathological and serological analysis was performed in five African migrants who developed an acute viral myositis complicated by rhabdomyolysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Muscle biopsies clearly documented an inflammatory myopathy with histological features similar to polymyositis including CD8+ T cells surrounding and invading nonnecrotic muscle fibers, CD68+ macrophages and major histocompatibility complex class I antigen upregulation. In addition, positivity for myositis\u2010specific antibodies (MSA), in particular anti\u2010aminoacyl tRNA synthetases, was found in the serum of two patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study demonstrated that T\u2010cell mediated injury occurs in muscle of patients with acute viral myositis, and that MSA may be present in the serum of these patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.26679","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T21:42:37Z","timestamp":1566596557000},"page":"586-590","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Benign acute viral myositis in African migrants: A clinical, serological, and pathological study"],"prefix":"10.1002","volume":"60","author":[{"given":"Elia","family":"Pancheri","sequence":"first","affiliation":[{"name":"Department of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Neurology University of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimiliano","family":"Lanzafame","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Infectious Diseases and Tropical medicine Section University of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Zam\u00f2","sequence":"additional","affiliation":[{"name":"Department of Pathology and Diagnostics, Section of Pathology University of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Angheben","sequence":"additional","affiliation":[{"name":"Centre for Tropical Diseases Sacro Cuore\u2010Don Calabria Hospital  Negrar Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Sartoris","sequence":"additional","affiliation":[{"name":"Department of Medicine, Immunology Section University of Verona  Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Zorzi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Diagnostics, Virology and Microbiology Unit University of Verona  Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marzia","family":"Boaretti","sequence":"additional","affiliation":[{"name":"Department of Pathology and Diagnostics, Virology and Microbiology Unit University of Verona  Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Signoretto","sequence":"additional","affiliation":[{"name":"Department of Pathology and Diagnostics, Virology and Microbiology Unit University of Verona  Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Guglielmi","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Neurology University of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Neurology University of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Tonin","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Neurology University of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Vattemi","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Neurology University of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200110000-00007"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00001-08"},{"key":"e_1_2_10_4_1","first-page":"1389","volume-title":"Myology","author":"Dalakas MC","year":"2004"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1402225"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.13357"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-004-4003-2"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1982.00510170003001"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/15513818309048284"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13317-014-0060-4"}],"container-title":["Muscle &amp; 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