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In recent years, several disorders have unexpectedly been reported in association with SFN, on clinical grounds and complementary investigations, including quantitative sensory testing, intraepidermal nerve fiber density and confocal corneal microscopy. Knowledge of these disorders is important in clinical practice as increased awareness enables prompt diagnosis of SFN in these settings and early optimal therapeutic management of affected patients. Furthermore, these new developments may lead to a better understanding of the pathophysiologic mechanisms underlying SFN in these different disorders as well as, in some cases, an expanded spectrum of affected organs and systems. This article reviews these reported associations, their possible pathophysiologic bases, and the potential resulting management implications.<\/jats:p>","DOI":"10.1002\/mus.26808","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T06:04:56Z","timestamp":1579068296000},"page":"167-175","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Small fiber neuropathy in unexpected clinical settings: a review"],"prefix":"10.1002","volume":"62","author":[{"given":"Majid","family":"Ghasemi","sequence":"first","affiliation":[{"name":"Regional Neuromuscular Service University Hospitals Birmingham  Birmingham United Kingdom"},{"name":"Department of Neurology, School of Medicine Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf A.","family":"Rajabally","sequence":"additional","affiliation":[{"name":"Regional Neuromuscular 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