{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T03:49:40Z","timestamp":1784087380511,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T00:00:00Z","timestamp":1581379200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Immobility of the upper limbs has been associated with reduction of F\u2010wave frequency. However, there are no similar studies on lower limb (LL) F\u2010waves. We investigated the impact of LL rest on F\u2010wave and H\u2010reflex parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The LLs of 14 healthy participants were studied after 90\u2009minutes rest. F\u2010waves (frequency, latencies, chronodispersion, and mean amplitude) and H\u2010reflexes (latency and recruitment curve) were investigated bilaterally. In seven participants the protocol was repeated, but the temperature of one limb was reduced.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Immobility only changed F\u2010wave latencies, which increased significantly (mean value of 2\u2009ms, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). Limb cooling did not influence results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Contrary to what occurred in cervical lower motor neurons (LMN), LL LMNs did not show a reduced F\u2010wave response to immobility, but their latency increased significantly. This could have been due to reduced Renshaw inhibition of small LMNs, thus facilitating their response to antidromic stimulation and causing delayed late responses.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.26817","type":"journal-article","created":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T10:20:41Z","timestamp":1580379641000},"page":"480-484","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Immobility and F\u2010waves: Impact on lower motor neuron excitability"],"prefix":"10.1002","volume":"61","author":[{"given":"Mariana","family":"Pereira","sequence":"first","affiliation":[{"name":"Instituto de Fisiologia, Instituto de Medicina Molecular, Faculdade de Medicina Univeridade de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8717-8914","authenticated-orcid":false,"given":"Michael","family":"Swash","sequence":"additional","affiliation":[{"name":"Instituto de Fisiologia, Instituto de Medicina Molecular, Faculdade de Medicina Univeridade de Lisboa  Lisbon Portugal"},{"name":"Department of Neurology and Neuroscience, Barts and the London School of Medicine Queen Mary University of London and Royal London Hospital  United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7556-0158","authenticated-orcid":false,"given":"Mamede","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Instituto de Fisiologia, Instituto de Medicina Molecular, Faculdade de Medicina Univeridade de Lisboa  Lisbon Portugal"},{"name":"Department of Neurosciences and Mental Health Hospital de Santa Maria, Centro Hospitalar Universit\u00e1rio de Lisboa Norte  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,11]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"265","article-title":"Electrophysiological studies of nerve and reflex in normal man. Identification of certain reflexes in the electromyogram and the conduction velocity of peripheral nerves","volume":"86","author":"Magladery JW","year":"1950","journal-title":"Bull Johns Hopkins Hosp."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.17.2.147"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880080113"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2007.49"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00363548"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1983.sp014732"},{"key":"e_1_2_9_8_1","first-page":"213","article-title":"Effect of sustained volitional muscle relaxation on the excitability of anterior horn cells: comparison between the F wave and MEP","volume":"32","author":"Okada F","year":"2004","journal-title":"Jpn J Clin Neurophysiol."},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2007.11.179"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20936"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2010.12.041"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0924-980X(95)00194-P"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-980X(97)00024-6"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(02)00009-3"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/146608202760834139"},{"key":"e_1_2_9_16_1","first-page":"89","article-title":"Excitability of the anterior horn cells after volitional inactivity of soleus muscle: H reflex study","volume":"34","author":"Yanagisawa T","year":"2006","journal-title":"Jpn J Clin Neurophysiol."},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.026526"},{"key":"e_1_2_9_18_1","volume-title":"The Circuitry of the Human Spinal Cord\u2014Its Role in Motor Control and Movement Disorders","author":"Pierrot\u2010Deseilligny E","year":"2012"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2018.07.002"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(03)00028-2"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/111.1.207"},{"key":"e_1_2_9_22_1","volume-title":"Nerves and Nerve Injuries","author":"Sunderland S","year":"1968"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/114.4.1771"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1941.4.2.167"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1961.sp006822"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1978.sp012422"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199607000-00018"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2004.00372.x"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.26817","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.26817","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mus.26817","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.26817","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T19:42:43Z","timestamp":1694029363000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.26817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,11]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["10.1002\/mus.26817"],"URL":"https:\/\/doi.org\/10.1002\/mus.26817","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,11]]},"assertion":[{"value":"2019-08-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}