{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T19:15:56Z","timestamp":1778786156826,"version":"3.51.4"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T00:00:00Z","timestamp":1596585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The purpose of this study was to investigate in vivo median nerve longitudinal mobility in different segments of the carpal tunnel associated with active finger motion in carpal tunnel syndrome (CTS) patients in a comparison with healthy controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eleven healthy volunteers and 11 CTS patients participated in this study. Dynamic ultrasound images captured location\u2010dependent longitudinal median nerve mobility within the carpal tunnel during finger flexion at the metacarpophalangeal joints using a speckle cross\u2010correlation algorithm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median nerve longitudinal mobility in the carpal tunnel was significantly smaller in CTS patients (0.0037\u2009\u00b1\u20090.0011\u2009mm\/degree) compared with controls (0.0082\u2009\u00b1\u20090.0026\u2009mm\/degree) (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05), especially in the proximal (0.0064 vs 0.0132\u2009mm\/degree on average) and middle (0.0033 vs 0.0074\u2009mm\/degree on average) carpal tunnel sections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Median nerve mobility can potentially serve as a biomechanical marker when diagnosing CTS, or when assessing the effectiveness of surgical and conservative treatments.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27017","type":"journal-article","created":{"date-parts":[[2020,7,9]],"date-time":"2020-07-09T13:05:48Z","timestamp":1594299948000},"page":"522-527","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["<scp>Location\u2010dependent<\/scp> change of median nerve mobility in the carpal tunnel of patients with carpal tunnel syndrome"],"prefix":"10.1002","volume":"62","author":[{"given":"Yifei","family":"Yao","sequence":"first","affiliation":[{"name":"Hand Research Laboratory, Department of Biomedical Engineering, Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Grandy","sequence":"additional","affiliation":[{"name":"Hand Research Laboratory, Department of Biomedical Engineering, Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J.","family":"Evans","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"William H.","family":"Seitz","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9636-7012","authenticated-orcid":false,"given":"Zong\u2010Ming","family":"Li","sequence":"additional","affiliation":[{"name":"Hand Research Laboratory, Department of Biomedical Engineering, Cleveland Clinic  Cleveland Ohio USA"},{"name":"Department of Orthopedic Surgery, Cleveland Clinic  Cleveland Ohio USA"},{"name":"Department of Physical Medicine and Rehabilitation, Cleveland Clinic  Cleveland Ohio USA"},{"name":"Department of Orthopaedic Surgery University of Arizona  Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,8,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2013.12.012"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/86.1.92"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.061804"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(97)80118-9"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0147051"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.39.6.566"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(94)90087-6"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880180713"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199612000-00013"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.orthres.2004.03.005"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0266-7681(92)90091-F"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-009-1416-x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-7681(05)80153-6"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037081"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22462"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22909"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.02.015"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2014.02.024"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-7681(03)00107-4"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199311000-00002"},{"key":"e_1_2_7_22_1","doi-asserted-by":"crossref","unstructured":"MarquardtTL GabraJN LiZM. 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