{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:58:52Z","timestamp":1791939532327,"version":"4.3.4"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,9,20]],"date-time":"2020-09-20T00:00:00Z","timestamp":1600560000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["NIH P30 AR057230"],"award-info":[{"award-number":["NIH P30 AR057230"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"publisher","award":["603685"],"award-info":[{"award-number":["603685"]}],"id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005693","name":"Parent Project Muscular Dystrophy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005693","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Serial muscle biopsies within clinical trials for Duchenne muscular dystrophy (DMD) are critical to document therapeutic responses. Less invasive means of sampling muscle are needed. We analyzed a retrospective consecutive case\u2010series cohort of vacuum\u2010assisted core needle muscle biopsy procedures performed on healthy and dystrophic individuals at a single institution assessing for safety and reliability of obtaining sufficient high\u2010quality biopsy tissue for histologic assessment in adult and pediatric subjects. Of 471 muscle cores from 128 biopsy procedures, 377\u2010550\u2009mg of total muscle tissue was obtained per procedure with mean core weight of 129\u2009mg (SD, 25.1\u2009mg). All biopsies were adequate for histological assessment. There were no significant adverse events. This core needle biopsy approach, when combined with improved sample processing, provides a safe means to consistently obtain muscle samples for diagnostic and clinical trial applications.<\/jats:p>","DOI":"10.1002\/mus.27041","type":"journal-article","created":{"date-parts":[[2020,8,20]],"date-time":"2020-08-20T21:52:06Z","timestamp":1597960326000},"page":"688-698","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["A well\u2010tolerated core needle muscle biopsy process suitable for children and adults"],"prefix":"10.1002","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9896-9551","authenticated-orcid":false,"given":"Florian","family":"Barthelemy","sequence":"first","affiliation":[{"name":"Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3988-9324","authenticated-orcid":false,"given":"Jeremy D.","family":"Woods","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"Nieves\u2010Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, David Geffen School of Medicine University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie D.","family":"Douine","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, David Geffen School of Medicine University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2483-3205","authenticated-orcid":false,"given":"Richard","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, David Geffen School of Medicine University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8460-8616","authenticated-orcid":false,"given":"Jonathan","family":"Wanagat","sequence":"additional","affiliation":[{"name":"Department of Medicine David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Carrie","family":"Miceli","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine and College of Letters and Sciences University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley F.","family":"Nelson","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, David Geffen School of Medicine University of California, Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,20]]},"reference":[{"issue":"363","key":"e_1_2_14_2_1","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1136\/bmj.2.363.541","article-title":"The pathology of paralysis with muscular degeneration (paralysie myosclerotique), or paralysis with apparent hypertrophy","volume":"2","author":"Duchenne GB","year":"1867","journal-title":"Br Med J"},{"issue":"7","key":"e_1_2_14_3_1","first-page":"B21","article-title":"Molecular genetics of Duchenne and Becker muscular dystrophy: emphasis on improved diagnosis","volume":"35","author":"Kunkel LM","year":"1989","journal-title":"Clin Chem"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmoldx.2016.05.003"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2015-103387"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-4685-GMB-2016-0019"},{"issue":"10","key":"e_1_2_14_7_1","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.nmd.2018.06.009","article-title":"Personalized gene and cell therapy for Duchenne muscular dystrophy","volume":"28","author":"Barth\u00e9l\u00e9my F","year":"2016","journal-title":"Neuromuscul Disord"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005680"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000015858"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2014.08.002"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2017.06.006"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21945"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2012.06.006"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2018.02.006"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25201"},{"issue":"1","key":"e_1_2_14_16_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7863\/jum.2006.25.1.1","article-title":"Sonographically guided percutaneous muscle biopsy in diagnosis of neuromuscular disease: a useful alternative to open surgical biopsy","volume":"25","author":"O\u02bcSullivan PJ","year":"2006","journal-title":"J Ultrasound Med"},{"issue":"3","key":"e_1_2_14_17_1","first-page":"13","article-title":"Office based muscle biopsy using Vacora\u2122 vacuum assisted biopsy system","volume":"41","author":"Akarolo\u2010Anthony SN","year":"2012","journal-title":"Afr J Med Med Sci"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2017.04.003"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2018.05.076"},{"issue":"5","key":"e_1_2_14_20_1","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1177\/00220345820610051301","article-title":"Mechanism of epinephrine enhancement of lidocaine\u2010induced skeletal muscle necrosis","volume":"61","author":"Yagiela JA","year":"1982","journal-title":"J Dent Res"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2016.09.002"},{"key":"e_1_2_14_22_1","unstructured":"Butterfly iQ.https:\/\/www.butterflynetwork.com. 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