{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T23:23:17Z","timestamp":1784935397831,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Introduction:<\/jats:bold> This series characterises nine patients with neurohistopathologically proven peripheral nerve neurolymphomatosis. <jats:bold>Methods:<\/jats:bold> A search of the hospital neuropathology database from 2002 to 2019 identified biopsy proven cases. Clinical data, investigation modalities, treatments, and outcomes were collated. Median age at neuropathy onset was 47\u2009y, the neuropathy commonly as the initial lymphoma disease manifestation. Most (8\/9) presented with painful asymmetrical sensory disturbance, with additional cranial nerve involvement in three. Neurophysiology typically demonstrated multiple axonal mononeuropathies. Cerebrospinal fluid protein was often raised (6\/8). Magnetic resonance imaging suggested peripheral nerve infiltration in 6\/9 and positron emission tomography CT in 4\/9. Bone marrow biopsy was abnormal in 6\/8. Treatment involved systemic or intrathecal chemotherapy and radiotherapy. Median survival was 23\u2009mo. <jats:bold>Discussion:<\/jats:bold> Neurolymphomatosis is a rare but important cause of neuropathy, particularly in those lacking systemic evidence of lymphoma as correct aggressive treatment can prolong survival. Nerve biopsy is essential to classify lymphoma type and rule out alternatives.<\/jats:p>","DOI":"10.1002\/mus.27045","type":"journal-article","created":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T18:54:15Z","timestamp":1597258455000},"page":"617-625","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Peripheral nerve neurolymphomatosis: Clinical features, treatment, and outcomes"],"prefix":"10.1002","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2102-6053","authenticated-orcid":false,"given":"Stephen","family":"Keddie","sequence":"first","affiliation":[{"name":"Centre for Neuromuscular Disease, Department of Neuromuscular Diseases UCL Institute of Neurology, and National Hospital of Neurology and Neurosurgery  London UK"},{"name":"Neuroimmunology and CSF Laboratory Institute of Neurology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust  London 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