{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T12:34:58Z","timestamp":1781267698993,"version":"3.54.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study examines the correlation, and clinical meaningfulness, between reachable workspace outcome and reported activities of daily living (ADL) function of individuals with facioscapulohumeral dystrophy (FSHD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010one FSHD subjects with various disease severity (clinical severity scores 1\u20104) underwent reachable workspace evaluation and completed the Quality of Life in Neurological Disorders (NeuroQoL) upper extremity questionnaire. Spearman and receiver operator curve analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Moderate correlation was found between NeuroQoL scores and total (\u03c1 = 0.7609; <jats:italic>P<\/jats:italic> &lt;\u2009.01), and upper\u2010quadrants relative surface areas (RSAs) (\u03c1 = 0.6969; <jats:italic>P<\/jats:italic> &lt;\u2009.01). Five specific items (ie, shirt on, shirt off, use spoon, pull on pants, pick\u2010up clothes) demonstrated even higher correlations with total (\u03c1 = 0.8397; <jats:italic>P<\/jats:italic> &lt;\u2009.01) and above shoulder (\u03c1 = 0.8082; <jats:italic>P<\/jats:italic> &lt;\u2009.01) RSAs. A total RSA cuffoff value of 0.70 would achieve 100% sensitivity and 94% specificity (area under the curve = 0.975).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Reachable workspace values identify when individuals have difficulties performing ADLs at home. This information improves patient monitoring, and clinical decision making by enabling more timely recommendations for medications, assistive devices, or considerations for clinical trial enrollments.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27123","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T23:16:50Z","timestamp":1605914210000},"page":"250-257","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Motion sensor\u2010acquired reachable workspace correlates with patient\u2010reported upper extremity activities of daily living (<scp>ADL<\/scp>) function in facioscapulohumeral dystrophy"],"prefix":"10.1002","volume":"63","author":[{"given":"Maya N.","family":"Hatch","sequence":"first","affiliation":[{"name":"Department of Physical Medicine &amp; Rehabilitation University of California at Irvine School of Medicine  Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregorij","family":"Kurillo","sequence":"additional","affiliation":[{"name":"Department of Orthopedics\/Orthopedic Surgery University of California at San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicky","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine &amp; Rehabilitation University of California at Irvine School of Medicine  Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay J.","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine &amp; Rehabilitation University of California at Irvine School of Medicine  Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2014.948138"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5544-1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3233\/THC-130764"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2019.05.006"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24287"},{"key":"e_1_2_9_7_1","volume-title":"International Classification of Functioning, Disability and Health (ICF)","author":"World Health Organization","year":"2011"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199906)45:6<751::AID-ANA9>3.0.CO;2-M"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21671"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318258f744"},{"key":"e_1_2_9_11_1","article-title":"Validity, reliability, and sensitivity of a 3D vision sensor\u2010based upper extremity reachable workspace evaluation in neuromuscular diseases","volume":"5","author":"Han JJ","year":"2013","journal-title":"PLoS Curr"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.07.032"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22266"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/154596830101500312"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1991.tb01616.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2010.02820.x"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.1.38"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002060-199509001-00007"},{"key":"e_1_2_9_19_1","first-page":"8","article-title":"Upper vs lower extremity functional loss in neuromuscular disease","volume":"68","author":"Lord JP","year":"1987","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/74.3.253"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.3_Part_1.442"}],"container-title":["Muscle &amp; 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