{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:03:26Z","timestamp":1792724606667,"version":"4.5.0"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:00:00Z","timestamp":1616544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Oropharyngeal dysphagia is a clinical hallmark of idiopathic inflammatory myopathy (IIM). This study investigated predictors, outcome, and characteristics of oropharyngeal dysphagia in patients with different types of IIM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Flexible endoscopic evaluation of swallowing (FEES) videos of 71 IIM patients were retrospectively analyzed for bolus spillage, penetration, aspiration, and pharyngeal residue. Based on these findings, dysphagia severity was rated. Regression analyses were performed to investigate demographic and disease\u2010specific predictors of dysphagia severity and pneumonia as outcome\u2010relevant complications of dysphagia. A score was developed to rate the quality of the endoscopic white\u2010out as a surrogate marker for pharyngeal muscle weakness with consecutive residue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our analysis revealed no independent predictors of dysphagia severity. Dysphagia severity, however, was an independent predictor for pneumonia, which occurred in 24% of patients. Pharyngeal residue with risk of postdeglutitive aspiration was the most common dysphagia pattern. Attenuation of the endoscopic white\u2010out was related to residue severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Dysphagia in IIM assessed with FEES is associated with relevant complications, such as aspiration pneumonia, and must be considered independently of peripheral muscle weakness and disease duration. Swallowing impairment mainly presents with pharyngeal residue. The quality of the white\u2010out may serve as a semi\u2010quantitative surrogate marker for pharyngeal contractility.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27225","type":"journal-article","created":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T18:19:48Z","timestamp":1615573188000},"page":"874-880","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Predictors, outcome and characteristics of oropharyngeal dysphagia in idiopathic inflammatory myopathy"],"prefix":"10.1002","volume":"63","author":[{"given":"Bendix","family":"Labeit","sequence":"first","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ksenia","family":"Perlova","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Pawlitzki","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Ruck","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Muhle","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inga","family":"Claus","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Suntrup\u2010Krueger","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinz","family":"Wiendl","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Dziewas","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Warnecke","sequence":"additional","affiliation":[{"name":"Department of Neurology with Institute of Translational Neurology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2013.09.006"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2017.09.006"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2017-000507"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4065\/82.4.441"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000109755.65914.5e"},{"issue":"3","key":"e_1_2_10_7_1","first-page":"263","article-title":"Long\u2010term prognosis of 69 patients with dermatomyositis or polymyositis","volume":"14","author":"Maugars YM","year":"1996","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0000000000000365"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-011-0814-y"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem131"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003337"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42466-019-0021-5"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-018-9961-0"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9072150"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23060"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009740903555366"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr213"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00739"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000493371"},{"issue":"10","key":"e_1_2_10_20_1","first-page":"2230","article-title":"Polymyositis and dermatomyositis: short term and longterm outcome, and predictive factors of prognosis","volume":"28","author":"Marie I","year":"2001","journal-title":"J Rheumatol"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780280303"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3233\/JND-150138"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm16028"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000491"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01321780"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4260501"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00334-4"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5229-9"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2004.02.024"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-011-9384-7"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2017.07.031"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.4.471"},{"issue":"6","key":"e_1_2_10_33_1","doi-asserted-by":"crossref","first-page":"e876","DOI":"10.1212\/WNL.0000000000011350","article-title":"Neurogenic dysphagia: systematic review and proposal of a classification system","volume":"96","author":"Warnecke T","year":"2021","journal-title":"Neurology"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0000000000001354"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13690"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.61.5.491"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27225","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mus.27225","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:29:55Z","timestamp":1693355395000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.27225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,24]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1002\/mus.27225"],"URL":"https:\/\/doi.org\/10.1002\/mus.27225","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,24]]},"assertion":[{"value":"2020-09-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}