{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T03:58:02Z","timestamp":1775793482641,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T00:00:00Z","timestamp":1618790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>The aim of the study was to determine the association between the virtual Myasthenia Gravis Impairment Index (vMGII) with other patient\u2010reported outcomes (PROs) of myasthenia gravis (MG) and its usefulness in telephone consultations with MG patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective case series in which vMGII score along with virtual Single Simple Question (vSSQ), virtual Patient\u2010Acceptable Symptom State PASS (vPASS) response, and patient disease status based on Myathenia Gravis Foundation of America postintervention status were collected during telephone consultation along with the MGII, SSQ, and PASS responses during the preceding in\u2010person clinic visits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 214 patients, the mean difference of vMGII between the vPASS \u201cYes\u201d and \u201cNo\u201d groups was \u221214.2\u2009\u00b1\u20091.4 (95% confidence interval, \u221216.9 to \u221211.3; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) with mean vMGII for vPASS \u201cYes\u201d group being 6.4\u2009\u00b1\u20097.7 and vPASS \u201cNo\u201d being 20.5\u2009\u00b1\u200911.5. A vMGII of 11.5 or higher predicted vPASS \u201cyes\u201d response with a sensitivity of 78.7% and specificity of 81.4%. A strong negative correlation was found between the vMGII and vSSQ (r\u00a0=\u00a0\u2212.667; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). The mean vMGII was 0.48\u2009\u00b1\u20091.42 for patients in remission, and 9.31\u2009\u00b1\u200910.93 for improved, 9.32\u2009\u00b1\u20098.79 for stable, and 22.58\u2009\u00b1\u200914.04 for worsened groups (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). These associations were the same as those obtained during the preceding in\u2010person clinic visit and the direction of change in MGII scores also indicated change in disease status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>vMGII is an effective measure to assess an MG patient's disease status in telephone consultations and relates well with other PRO measures. The vMGII remains reliable for assessing MG disease status even with removal of the physical examination component.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27243","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T11:30:22Z","timestamp":1617276622000},"page":"831-836","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Telephone consultation for myasthenia gravis care during the <scp>COVID<\/scp>\u201019 pandemic: Assessment of a novel virtual myasthenia gravis index"],"prefix":"10.1002","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7360-417X","authenticated-orcid":false,"given":"Deepak","family":"Menon","sequence":"first","affiliation":[{"name":"Ellen &amp; Martin Prosserman Centre for Neuromuscular Diseases, University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Alnajjar","sequence":"additional","affiliation":[{"name":"Ellen &amp; Martin Prosserman Centre for Neuromuscular Diseases, University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5546-0221","authenticated-orcid":false,"given":"Carolina","family":"Barnett","sequence":"additional","affiliation":[{"name":"Ellen &amp; Martin Prosserman Centre for Neuromuscular Diseases, University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joy","family":"Vijayan","sequence":"additional","affiliation":[{"name":"Ellen &amp; Martin Prosserman Centre for Neuromuscular Diseases, University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"Katzberg","sequence":"additional","affiliation":[{"name":"Ellen &amp; Martin Prosserman Centre for Neuromuscular Diseases, University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davood","family":"Fathi","sequence":"additional","affiliation":[{"name":"Ellen &amp; Martin Prosserman Centre for Neuromuscular Diseases, University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Alcantara","sequence":"additional","affiliation":[{"name":"Ellen &amp; Martin Prosserman Centre for Neuromuscular Diseases, University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Bril","sequence":"additional","affiliation":[{"name":"Ellen &amp; Martin Prosserman Centre for Neuromuscular Diseases, University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,4,19]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Telemedicine and virtual care guidelines for health professionals.R Coll Phys Surg Canada. 2020.http:\/\/www.royalcollege.ca\/rcsite\/documents\/about\/covid-19-resources-telemedicine-virtual-care-e. 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