{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:56:44Z","timestamp":1784689004915,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The Duchenne Video Assessment (DVA) assesses quality of movement as an indication of Duchenne muscular dystrophy (DMD) disease severity. Caregivers video record patients performing home\u2010based movement tasks using a mobile application, and physical therapists (PTs) rate the videos using scorecards with prespecified compensatory movement criteria. Reliability and construct validity of the DVA were tested using video and Pediatric Outcomes Data Collection Instrument (PODCI) data from patients with DMD and healthy controls from a separate study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifteen PTs were trained and certified as DVA raters. All raters scored videos of five subjects performing each movement task; nine raters rescored the same videos four weeks later. Three raters scored videos from an average of 25 subjects for each movement task. Aggregate scores were used to test construct validity. An expert DMD clinician assigned each video to a severity group for known\u2010groups analyses. Differences between rater scores across severity groups were tested and correlations between DVA and PODCI scores were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Inter\u2010rater reliability (intraclass correlation coefficient [ICC]) between all 15 raters ranged from 0.70 to 0.97 for all movement tasks. Mean intra\u2010rater reliability ICC for nine raters ranged from 0.82 to 0.98 for all movement tasks. There were statistically significant differences between known severity groups for all movement tasks. The DVA correlated strongly with related PODCI constructs of physical function and weakly with unrelated constructs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The DVA was found to be a reliable and valid tool for measuring quality of movement as an indication of disease severity.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27335","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T20:53:09Z","timestamp":1622753589000},"page":"180-189","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Reliability and construct validity of the Duchenne Video Assessment"],"prefix":"10.1002","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4769-1617","authenticated-orcid":false,"given":"Marielle G.","family":"Contesse","sequence":"first","affiliation":[{"name":"Casimir  Plymouth Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber T. L.","family":"Sapp","sequence":"additional","affiliation":[{"name":"Casimir  Plymouth Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan D.","family":"Apkon","sequence":"additional","affiliation":[{"name":"Children's Hospital Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4206-0557","authenticated-orcid":false,"given":"Linda P.","family":"Lowes","sequence":"additional","affiliation":[{"name":"Nationwide Children's Hospital  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Dalle Pazze","sequence":"additional","affiliation":[{"name":"Charley's Fund  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mindy G.","family":"Leffler","sequence":"additional","affiliation":[{"name":"Casimir  Plymouth Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.13634"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2018.05.013"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2010.03.005"},{"key":"e_1_2_10_5_1","first-page":"86","article-title":"Use of the six\u2010minute walk distance (6MWD) across Duchenne muscular dystrophy (DMD) studies (P3.121)","author":"McDonald C","year":"2016","journal-title":"Neurology"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26161"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","first-page":"e0221398","DOI":"10.1371\/journal.pone.0221398","article-title":"Evaluation of balance recovery stability from unpredictable perturbations through the compensatory arm and leg movements (CALM) scale","volume":"14","author":"Souza CR","year":"2019","journal-title":"PLoS One"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afl078"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/77.5.488"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(95)00053-4"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pri.520"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0199223"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0221097"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-019-02245-2"},{"key":"e_1_2_10_15_1","unstructured":"LefflerMG ContesseMG StauntonH.Home\u2010based video assessment of the quality of movement of patients with Duchenne: interviews with physical therapists to inform task selection [abstract]. In: MDA Clinical and Scientific Conference; 2019 Apr 13\u201317; Orlando FL Abstract P.161."},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-020-01550-1"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.2.420"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcm.2016.02.012"},{"key":"e_1_2_10_19_1","first-page":"614","article-title":"Biostatistics 104: correlational analysis","volume":"44","author":"Chan YH","year":"2003","journal-title":"Singapore Med J"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjem.2018.08.001"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/140381902317303195"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/64.1.41"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2013.11.014"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073810371509"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2015.06.416"},{"key":"e_1_2_10_26_1","volume-title":"Duchenne Muscular Dystrophy and Related Dystrophinopathies: Developing Drugs for Treatment","author":"U.S. Food & Drug Administration","year":"2018"},{"key":"e_1_2_10_27_1","volume-title":"Guideline on the Clinical Investigation of Medicinal Products for the Treatment of Duchenne and Becker Muscular Dystrophy","author":"European Medicines Agency","year":"2015"},{"key":"e_1_2_10_28_1","first-page":"1","article-title":"Biomarkers of Duchenne muscular dystrophy: current findings","volume":"8","author":"Szigyarto CA\u2010K","year":"2018","journal-title":"Degener Neurol Neuromuscul Dis"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2014.03.006"},{"key":"e_1_2_10_30_1","volume-title":"Surrogate Endpoint Resources for Drug and Biologic Development","author":"U.S. Food & Drug Administration","year":"2018"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27335","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mus.27335","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T17:52:14Z","timestamp":1693331534000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.27335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,16]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1002\/mus.27335"],"URL":"https:\/\/doi.org\/10.1002\/mus.27335","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,16]]},"assertion":[{"value":"2020-08-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}