{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T04:01:59Z","timestamp":1783656119409,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007197","name":"U.S. Public Health Service","doi-asserted-by":"publisher","award":["K24NS059892"],"award-info":[{"award-number":["K24NS059892"]}],"id":[{"id":"10.13039\/100007197","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007197","name":"U.S. Public Health Service","doi-asserted-by":"publisher","award":["R01NS093653"],"award-info":[{"award-number":["R01NS093653"]}],"id":[{"id":"10.13039\/100007197","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>Isolated injuries to the lateral cutaneous nerve of the calf (LCNC) branch of the common peroneal nerve can cause obscure chronic posterolateral knee and upper calf pain and sensory symptoms. Routine examination and electrodiagnostic testing do not detect them because the LCNC has no motor distribution and it is not interrogated by the typical peroneal nerve conduction study. There are only about 10 prior cases, thus scant physician awareness, so most LCNC injuries remain misdiagnosed or undiagnosed, hindering care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We extracted pertinent records from seven patients with unexplained posterolateral knee\/calf pain, six labeled as complex regional pain syndrome, to investigate for mononeuropathies. Patients were asked to outline their skin area with abnormal responses to pin self\u2010examination independently. Three underwent an LCNC\u2010specific electrodiagnostic study, and two had skin\u2010biopsy epidermal innervation measured. Cadaver dissection of the posterior knee nerves helped identify potential entrapment sites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Initiating events included knee surgery (three), bracing (one), extensive kneeling (one), and other knee trauma. All pin\u2010outlines included the published LCNC neurotome. One oftwo LCNC\u2010specific electrodiagnostic studies revealed unilaterally absent potentials. Longitudinal, controlled skin biopsies documented profound LCNC\u2010neurotome denervation then re\u2010innervation contemporaneous with symptom recovery. Cadaver dissection identified the LCNC traversing through the dense fascia of the proximolateral gastrocnemius muscle insertion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Isolated LCNC mononeuropathy can cause unexplained posterolateral knee\/calf pain syndromes. This series characterizes presentations and supports patient pin\u2010mappings as a sensitive, globally available, low\u2010cost diagnostic aid. Improved recognition may facilitate more rapid, accurate diagnosis and, thus, optimize management and improve outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27367","type":"journal-article","created":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T07:34:52Z","timestamp":1625211292000},"page":"494-499","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Characterization of mononeuropathy of the lateral cutaneous nerve of the calf"],"prefix":"10.1002","volume":"64","author":[{"given":"Anne Louise","family":"Oaklander","sequence":"first","affiliation":[{"name":"Nerve Unit, Departments of Neurology and Pathology (Neuropathology) Massachusetts General Hospital, Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trudy","family":"Van Houten","sequence":"additional","affiliation":[{"name":"Department of Radiology Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2348-5138","authenticated-orcid":false,"given":"A. Sassan","family":"Sabouri","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Critical Care and Pain Medicine Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2006.09.008"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410040520"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02229228"},{"key":"e_1_2_10_5_1","volume-title":"Focal Peripheral Neuropathies","author":"Stewart JD","year":"2000"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20595"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100033813"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-008847"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2010.02.003"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200207000-00039"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2007.04.005"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12336"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000003765"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1249\/JSR.0000000000000083"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.J.00842"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1268070"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2010.03.002"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000185338.28038.96"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000183"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1972.04180100035010"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.oa.2018-0039"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.93B7.26549"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/BLO.0b013e31806008d9"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199411000-00016"},{"key":"e_1_2_10_25_1","first-page":"88","article-title":"Injury to infrapatellar branch of saphenous nerve in arthroscopic knee surgery","volume":"320","author":"Mochida H","year":"1995","journal-title":"Clin Orthop"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.140.67"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4598(200008)23:8<1277::AID-MUS19>3.0.CO;2-4"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18-21-08947.1998"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000070781.92512.A4"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70251-0"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330150115"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.10016"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12565-013-0195-9"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000001628"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182818cd4"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2014.01.030"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e318174e569"}],"container-title":["Muscle &amp; 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