{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:19:03Z","timestamp":1791908343929,"version":"4.3.4"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,7,27]],"date-time":"2021-07-27T00:00:00Z","timestamp":1627344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>Chronic inflammatory demyelinating polyneuropathy (CIDP) may be rarely preceded by infection. A causative link remains unproven, in contrast to Guillain\u2010Barr\u00e9 syndrome (GBS), which is commonly postinfectious with well\u2010demonstrated pathophysiological mechanisms of molecular mimicry following <jats:italic>Campylobacter jejuni<\/jats:italic> enteritis. Uncommonly, infections are reported before the onset of CIDP. In this study we aimed to determine the frequency and characteristics of CIDP occurring after antecedent infections or vaccinations in two large European cohorts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed the records of 268 subjects with \u201cdefinite\u201d or \u201cprobable\u201d CIDP from the Inflammatory Neuropathy Clinic, Birmingham, UK (129 subjects), and from the Serbian national CIDP database (139 subjects).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010five of 268 (9.3%) subjects had a respiratory or gastrointestinal infection in the 6\u2009weeks preceding CIDP onset, and 3 of 268 (1.1%) had received an influenza vaccination. CIDP disease onset occurred at a younger age (mean [standard deviation], 44.25\u00a0[17.36] years vs 54.05\u00a0[15.19] years; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.005) and acute\u2010onset CIDP was more common (42.9% vs 12.1%; odds ratio, 5.46; 95% confidence interval, 2.35\u201012.68; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) in subjects with preceding infections or vaccinations. No differences in CIDP subtype, rates of cerebrospinal fluid protein level elevation, disability, or likelihood of treatment response, were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Antecedent infections or vaccinations may precede about 10% of cases of CIDP and are more common in younger subjects. Acute\u2010onset CIDP is more frequent after antecedent events. These findings may suggest specific pathophysiological mechanisms in such cases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27374","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T11:26:20Z","timestamp":1626348380000},"page":"657-661","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Antecedent infections and vaccinations in chronic inflammatory demyelinating polyneuropathy: A European collaborative study"],"prefix":"10.1002","volume":"64","author":[{"given":"Yusuf A.","family":"Rajabally","sequence":"first","affiliation":[{"name":"Inflammatory Neuropathy Clinic University Hospitals Birmingham  Birmingham UK"},{"name":"Aston Medical School Aston University  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2979-556X","authenticated-orcid":false,"given":"Stojan","family":"Peric","sequence":"additional","affiliation":[{"name":"Neurology Clinic, Clinical Centre of Serbia, School of Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Bozovic","sequence":"additional","affiliation":[{"name":"Neurology Clinic, Clinical Centre of Serbia, School of Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lay K.","family":"Loo","sequence":"additional","affiliation":[{"name":"Inflammatory Neuropathy Clinic University Hospitals Birmingham  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aida","family":"Kalac","sequence":"additional","affiliation":[{"name":"Neurology Clinic, Clinical Centre of Montenegro  Podgorica Montenegro"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksa","family":"Palibrk","sequence":"additional","affiliation":[{"name":"Neurology Clinic, Clinical Centre of Serbia, School of Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Basta","sequence":"additional","affiliation":[{"name":"Neurology Clinic, Clinical Centre of Serbia, School of Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.4.1110"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00339-1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1978.00500320029007"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/110.6.1617"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.11.2202"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199708)20:8<1008::AID-MUS11>3.0.CO;2-R"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.2.321"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.114868"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2009.00243.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14044"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02930.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2009.194324"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.27250"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756286420952901"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21480"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21206"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0028-3886.86547"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir074"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1212.051032"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2017.32.7.1154"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2013.01.056"},{"key":"e_1_2_9_23_1","first-page":"128","article-title":"The spectrum of acquired demyelinating polyradiculoneuropathy","volume":"94","author":"Hughes RA","year":"1994","journal-title":"Acta Neurol Belg."},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181e07d14"}],"container-title":["Muscle &amp; 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