{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:54:50Z","timestamp":1788317690677,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004243","name":"Prinses Beatrix Spierfonds","doi-asserted-by":"publisher","award":["W.OR16\u201005"],"award-info":[{"award-number":["W.OR16\u201005"]}],"id":[{"id":"10.13039\/501100004243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>Neuralgic amyotrophy (NA) is a multifocal neuropathy involving the nerves of the upper extremity, limiting functional capability and reducing range of motion. The reachable workspace (RWS) is a computerized three\u2010dimensinal analysis system that evaluates the relative surface area (RSA) of an individual's arm reachability and has shown utility in several neuromuscular disorders. The aims of this study were to examine the ability of the RWS to quantitatively detect limitations in upper extremity active range of motion in patients with NA, and correlate these with other upper extremity functional outcome measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010seven patients with NA and 25 healthy age\u2010 and sex\u2010matched controls were measured with the RWS. Study participants\u2019 RSAs were correlated with scores on the Shoulder Rating Questionnaire (SRQ), the Disabilities of Arm Shoulder and Hand (DASH) questionnaire, and upper extremity strength measurements using hand\u2010held dynamometry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with NA showed significantly lower values in the affected arm for all quadrants (except for the ipsilateral lower quadrant) and total RSA compared with controls (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001). We found moderate correlations between the reachable workspace, the DASH questionnaire result (r\u00a0=\u00a0\u22120.415), and serratus anterior muscle strength (<jats:italic>r<\/jats:italic>\u00a0=\u20090.414).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>RWS is able to detect limitations in active range of motion of the affected arm in patients with NA, and is moderately correlated with upper extremity functional measures. RWS can demonstrate impairment of the affected upper extremity in NA and it has potential as a clinical outcome measure.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27651","type":"journal-article","created":{"date-parts":[[2022,6,4]],"date-time":"2022-06-04T09:09:55Z","timestamp":1654333795000},"page":"282-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Reachable workspace analysis is a potential measurement for impairment of the upper extremity in neuralgic amyotrophy"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5553-9677","authenticated-orcid":false,"given":"Jos","family":"IJspeert","sequence":"first","affiliation":[{"name":"Department of Rehabilitation, Donders Institute for Brain, Cognition and Behavior Radboud University Medical Center  Nijmegen GA 6525 The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renee","family":"Lustenhouwer","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Donders Institute for Brain, Cognition and Behavior Radboud University Medical Center  Nijmegen GA 6525 The Netherlands"},{"name":"Donders Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behavior Radboud University  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renske M.","family":"Janssen","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Radboud Institute for Health Sciences Radboud University Medical Center  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay J.","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine &amp; Rehabilitation University of California Irvine School of Medicine  Irvine California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya N.","family":"Hatch","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine &amp; Rehabilitation University of California Irvine School of Medicine  Irvine California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Cameron","sequence":"additional","affiliation":[{"name":"Donders Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behavior Radboud University  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick C.","family":"Helmich","sequence":"additional","affiliation":[{"name":"Donders Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behavior Radboud University  Nijmegen The Netherlands"},{"name":"Department of Neurology, Donders Institute for Brain, Cognition and Behavior Radboud University Medical Center  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baziel","family":"van Engelen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Donders Institute for Brain, Cognition and Behavior Radboud University Medical Center  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"van der Wees","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Radboud Institute for Health Sciences Radboud University Medical Center  Nijmegen The Netherlands"},{"name":"Radboud University Medical Center, Radboud Institute for Health Sciences Scientific Institute for Quality of Healthcare  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C. H.","family":"Geurts","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Donders Institute for Brain, Cognition and Behavior Radboud University Medical Center  Nijmegen GA 6525 The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7839-8125","authenticated-orcid":false,"given":"Nens","family":"van Alfen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Donders Institute for Brain, Cognition and Behavior Radboud University Medical Center  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan T.","family":"Groothuis","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Donders Institute for Brain, Cognition and Behavior Radboud University Medical Center  Nijmegen GA 6525 The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0128361"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000968"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh722"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2012.07.014"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-130993"},{"key":"e_1_2_10_7_1","first-page":"306","article-title":"The reliability and concurrent validity of shoulder mobility measurements using a digital inclinometer and goniometer: a technical report","volume":"7","author":"Kolber MJ","year":"2012","journal-title":"Int J Sports Phys Ther."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.27123"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/09593980903094230"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3233\/THC-130764"},{"key":"e_1_2_10_11_1","article-title":"Validity, reliability, and sensitivity of a 3D vision sensor\u2010based upper extremity reachable workspace evaluation in neuromuscular diseases","volume":"5","author":"Han JJ","year":"2013","journal-title":"PLoS Curr."},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24287"},{"key":"e_1_2_10_13_1","first-page":"2","article-title":"Novel Kinect\u2010based method to assess 3D reachable workspace in musculoskeletal shoulder dysfunctions: case reports","volume":"3","author":"Reddy D","year":"2015","journal-title":"Int J Phys Med. Rehabil."},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24703"},{"key":"e_1_2_10_15_1","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1186\/s13063-019-3556-4","article-title":"NA\u2010CONTROL: a study protocol for a randomised controlled trial to compare specific outpatient rehabilitation that targets cerebral mechanisms through relearning motor control and uses self\u2010management strategies to improve functional capability of the upper extremity, to usual care in patients with neuralgic amyotrophy","volume":"20","author":"Lustenhouwer R","year":"2019","journal-title":"Trials."},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3932(71)90067-4"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2019.05.006"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1191\/0269215505cr811oa"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-1130(02)80006-0"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24396"},{"key":"e_1_2_10_21_1","first-page":"1","article-title":"Validity and reliability of serratus anterior hand held dynamometry","volume":"20","author":"IJspeert J","year":"2019","journal-title":"BMC Musculoskelet Disord."},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(97)90005-8"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1197\/j.jht.2005.07.003"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000002864"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2011.62"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2008.08.216"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199906)45:6<751::AID-ANA9>3.0.CO;2-M"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.1351892"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2020.02.011"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25172"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27651","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mus.27651","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27651","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T05:29:17Z","timestamp":1692682157000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.27651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,21]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1002\/mus.27651"],"URL":"https:\/\/doi.org\/10.1002\/mus.27651","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,21]]},"assertion":[{"value":"2021-12-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}