{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:23:30Z","timestamp":1790731410232,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T00:00:00Z","timestamp":1660003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2022,10]]},"abstract":"Abstract<\/jats:title>\n \n Introduction\/Aims<\/jats:title>\n Facioscapulohumeral muscular dystrophy (FSHD) causes weakness and secondary associations, such as respiratory complications and pain, that can be linked to abnormal sleep patterns. Limited studies have focused on sleep in FSHD. The purpose of this study was to identify the prevalence of, and clinical features associated with, self\u2010reported lowered sleep quality (SQ) and excessive daytime sleepiness (DS) in a large group of participants with FSHD.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n We conducted a prospective survey of individuals with self\u2010reported FSHD enrolled in the FSHD Society Registry. The survey consisted of demographic and clinical characteristics, the Pittsburgh Sleep Quality Index (PSQI), and the Epworth Sleepiness Scale. Descriptive statistics were evaluated, and associations between clinical characteristics and SQ and DS were explored using one\u2010way analysis of variance tests. Small effect size was identified as 0.01\u2009\u2265\u2009\u03b7\n 2<\/jats:sup>\n \u2009>\u20090.06, medium was 0.06\u2009\u2265\u2009\u03b7\n 2<\/jats:sup>\n \u2009>\u20090.14, and large was 0.14\u2009\u2265\u2009\u03b7\n 2<\/jats:sup>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Six hundred ninety individuals responded to the survey, equally distributed between men and women, and spanning the age range from under 12 to 74\u2009years of age or older. Sixty\u2010six percent of the respondents showed reduced SQ (PSQI >\u20095) (n\u00a0=\u00a0392; 95% confidence interval [CI], 62.4\u201070.0), and 15% showed excessive DS (>10) (n\u00a0=\u00a089; 95% CI, 12.2\u201017.9). There was a significant association between SQ and DS. Nocturnal pain had a large significant effect on lowering SQ (\n P<\/jats:italic>\n \u2009<\u2009.001, \u03b7\n 2<\/jats:sup>\n \u00a0=\u00a00.192). Factors including age and gender had minor effects on SQ.\n <\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n Physicians should monitor sleep quality of patients with FSHD as a routine part of care, with special attention to potentially modifiable factors. Future research should address the physiological effects of pain in sleep.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/mus.27688","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T04:54:24Z","timestamp":1658897664000},"page":"487-494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Self\u2010reported reduced sleep quality and excessive daytime sleepiness in facioscapulohumeral muscular dystrophy"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2466-5173","authenticated-orcid":false,"given":"Heloise M.","family":"Hoffmann","sequence":"first","affiliation":[{"name":"Community School of Naples Naples Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Malo\u2010Juvera","sequence":"additional","affiliation":[{"name":"University of North Carolina Wilmington Wilmington North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0790-5315","authenticated-orcid":false,"given":"Jeffrey M.","family":"Statland","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Kansas Medical Center Kansas City Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,9]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2019.02.006"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010015\u20101247\u20102"},{"key":"e_1_2_10_4_1","first-page":"1916","article-title":"Facioscapulohumeral muscular dystrophy","volume":"22","author":"Statland JM","year":"2016","journal-title":"Continuum."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.05.028"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2009.05.014"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010019\u201001843\u20101"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2013.06.642"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415\u2010017\u20108525\u20109"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pme.12054"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165\u20101781(89)90047\u20104"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/14.6.540"},{"key":"e_1_2_10_13_1","volume-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen J","year":"1988"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2016.03.008"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.08.153"},{"key":"e_1_2_10_16_1","first-page":"391","article-title":"Excessive daytime sleepiness","volume":"79","author":"Pagel JF","year":"2009","journal-title":"Am Fam Physician."}],"container-title":["Muscle & Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27688","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mus.27688","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27688","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T10:04:33Z","timestamp":1692612273000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.27688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,9]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/mus.27688"],"URL":"https:\/\/doi.org\/10.1002\/mus.27688","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,9]]},"assertion":[{"value":"2021-12-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}