{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T04:39:51Z","timestamp":1794026391289,"version":"4.8.0"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,10,25]],"date-time":"2022-10-25T00:00:00Z","timestamp":1666656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["National Center for Advancing Translational Scienc"],"award-info":[{"award-number":["National Center for Advancing Translational Scienc"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction\/Aims<\/jats:title>\n                    <jats:p>Hourglass\u2010like constrictions (HGCs) occur in neuralgic amyotrophy (NA), but the earliest time at which they can be recognized by imaging is poorly understood. We aimed to determine the prevalence of abnormal imaging findings in the acute phase of NA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Magnetic resonance neurography (MRN) and high\u2010resolution ultrasound (US) examinations were performed at five sites. The investigation included 39 patients with acute NA who underwent imaging within 31\u2009days of symptom onset. Correlation between imaging and electromyography (EMG) findings was measured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>US was performed in 29 patients and MRN in 23; 16 patients underwent US only, 10 MRN only, and 13 had both. US and MRN showed nerve abnormalities within 1\u00a0mo from NA onset in 90% of patients. HGCs were found in 74% (29\/39) of the patients: 4 within 1\u00a0wk, 8 within 2\u00a0wk, 5 within 3\u00a0wk, and 12 within 4\u00a0wk. The earliest HGC on US was found within 12\u2009h, and on MRN within 3\u2009days from symptom onset. MRN demonstrated a denervation edema pattern of affected muscles in 91% of the patients. The shortest time to observe an edema pattern on MRN was 8\u2009days. EMG was performed in 30 patients and revealed fibrillation potentials in affected muscles in 22 (73%). A denervation edema pattern on MRN was significantly associated with the presence of HGCs both on MRN and US, and with fibrillation potentials on EMG.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>In the early phase of NA, US and MRN are useful diagnostic techniques for demonstrating nerve abnormalities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.27732","type":"journal-article","created":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T09:46:58Z","timestamp":1665395218000},"page":"709-714","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Imaging of neuralgic amyotrophy in the acute phase"],"prefix":"10.1002","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8662-9656","authenticated-orcid":false,"given":"Paolo","family":"Ripellino","sequence":"first","affiliation":[{"name":"Department of Neurology Neurocenter of Southern Switzerland EOC  Lugano Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsuzsanna","family":"Ar\u00e1nyi","sequence":"additional","affiliation":[{"name":"Department of Neurology Semmelweis University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nens","family":"van Alfen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Ventura","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Neurocenter of Southern Switzerland EOC  Lugano Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u2010Kathrin","family":"Peyer","sequence":"additional","affiliation":[{"name":"Neuroliestal Praxis  Liestal Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Cianfoni","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Neurocenter of Southern Switzerland EOC  Lugano Switzerland"},{"name":"Department of Neuroradiology Inselspital  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Gobbi","sequence":"additional","affiliation":[{"name":"Department of Neurology Neurocenter of Southern Switzerland EOC  Lugano Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Pedrick","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9105-5415","authenticated-orcid":false,"given":"Darryl Brett","family":"Sneag","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25008"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2020-323164"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000968"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23310"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1955.18.1.65"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000000350"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24615"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25708"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25480"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26108"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26768"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2017.04.030"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26322"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25147"},{"key":"e_1_2_10_16_1","volume-title":"GeneReviews\u00ae 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