{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:42:37Z","timestamp":1747150957218,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:00:00Z","timestamp":1678320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2023,5]]},"abstract":"Abstract<\/jats:title>Introduction\/Aims<\/jats:title>Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is the most common form of Guillain\u2010Barr\u00e9 syndrome (GBS) in Western countries. However, electrophysiological descriptions of changes in abnormalities suggestive of demyelination after an AIDP episode are rare. We aimed to describe the clinical and electrophysiological features of AIDP patients after the acute episode, to investigate changes in abnormalities suggestive of demyelination and to compare with electrophysiological features of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).<\/jats:p><\/jats:sec>Methods<\/jats:title>We reviewed the clinical and electrophysiological characteristics of 61 patients followed at regular intervals after the AIDP episode.<\/jats:p><\/jats:sec>Results<\/jats:title>We detected early electrophysiological abnormalities from the first nerve conduction studies (NCS) performed before 3\u00a0wk. Abnormalities suggestive of demyelination worsened on subsequent examinations. This worsening continued after more than 3\u00a0mo of follow\u2010up for some parameters. We also found the persistence of abnormalities suggestive of demyelination for long periods after the acute episode, beyond 18\u2009mo of follow\u2010up, despite clinical improvement in most patients.<\/jats:p><\/jats:sec>Discussion<\/jats:title>In AIDP, NCS findings continue to worsen several weeks or even months after the onset of symptoms, and \u201cCIDP\u2010like\u201d abnormalities suggestive of demyelination may persist for a long period of time, in contrast to the existing literature and the usually favorable clinical course. Thus, the discovery of conduction abnormalities on NCS performed long after an AIDP should always be interpreted according to the clinical context and not systematically lead to a diagnosis of CIDP.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27803","type":"journal-article","created":{"date-parts":[[2023,2,23]],"date-time":"2023-02-23T04:43:35Z","timestamp":1677127415000},"page":"394-400","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Changes in electrophysiological findings suggestive of demyelination following Guillain\u2010Barr\u00e9<\/scp> syndrome: A retrospective study"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9522-9515","authenticated-orcid":false,"given":"Cl\u00e9ment","family":"Gu\u00e9my","sequence":"first","affiliation":[{"name":"Neurology Department Raymond\u2010Poincar\u00e9 Hospital Garches France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie\u2010Christine","family":"Durand","sequence":"additional","affiliation":[{"name":"Physiology Department Raymond\u2010Poincar\u00e9 Hospital Garches France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Brisset","sequence":"additional","affiliation":[{"name":"Neurology Department Raymond\u2010Poincar\u00e9 Hospital Garches France"},{"name":"Physiology Department Raymond\u2010Poincar\u00e9 Hospital Garches France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillaume","family":"Nicolas","sequence":"additional","affiliation":[{"name":"Neurology Department Raymond\u2010Poincar\u00e9 Hospital Garches France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,3,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awy232"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awt285"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410370704"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181e07d14"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21480"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.59.5.482"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24667"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880080609"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.34.5.607"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1986.tb03295.x"},{"key":"e_1_2_12_12_1","first-page":"205","article-title":"Motor and afferent nerve conduction in the Guillain\u2010Barr\u00e9\u2010Sthrol syndrome: a longitudinal study in five cases with different clinical features","volume":"6","author":"Bergamini L","year":"1966","journal-title":"Electromyography"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490360014004"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270707"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)92644-2"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199738687.003.0005"},{"volume-title":"S\u00e9miologie \u00e9lectrophysiologique","year":"1998","author":"Fournier E","key":"e_1_2_12_17_1"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-3787(05)85166-5"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02930.x"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004150170157"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.2.409"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(94)90010-8"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000149521.65474.83"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/111.2.405"}],"container-title":["Muscle & Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27803","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mus.27803","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27803","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T19:09:03Z","timestamp":1692472143000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.27803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,9]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1002\/mus.27803"],"URL":"https:\/\/doi.org\/10.1002\/mus.27803","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"type":"print","value":"0148-639X"},{"type":"electronic","value":"1097-4598"}],"subject":[],"published":{"date-parts":[[2023,3,9]]},"assertion":[{"value":"2022-07-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}