{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:03:15Z","timestamp":1788454995209,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T00:00:00Z","timestamp":1679961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003035","name":"Aase og Ejnar Danielsens Fond","doi-asserted-by":"publisher","award":["10\u2010002109"],"award-info":[{"award-number":["10\u2010002109"]}],"id":[{"id":"10.13039\/501100003035","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009899","name":"Bevica Fonden","doi-asserted-by":"publisher","award":["AU\u2010904020"],"award-info":[{"award-number":["AU\u2010904020"]}],"id":[{"id":"10.13039\/501100009899","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006197","name":"Fonden til L\u00e6gevidenskabens Fremme","doi-asserted-by":"publisher","award":["17\u2010L\u20100126"],"award-info":[{"award-number":["17\u2010L\u20100126"]}],"id":[{"id":"10.13039\/501100006197","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction\/Aims<\/jats:title>\n                    <jats:p>Guillain\u2010Barr\u00e9 syndrome (GBS) is a potentially life\u2010threatening disorder, and some patients may develop subsequent depression related to traumatic stress or permanent loss of motor function. We determined the short\u2010term (0 to 2\u2009years) and long\u2010term (&gt;2\u2009years) risk of depression after GBS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Individual\u2010level data from nationwide registries were linked in this population\u2010based cohort study of all first\u2010time hospital\u2010diagnosed GBS patients in Denmark between 2005 and 2016 and individuals from the general population. After exclusion of individuals with previous depression, we computed cumulative rates of depression, defined as either antidepressant drug prescription or depression hospital diagnosis. We used Cox regression analyses to calculate adjusted depression hazard ratios (HRs) after GBS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 853 incident GBS patients and recruited 8639 individuals from the general population. Depression within 2\u2009years was observed in 21.3% (95% confidence interval [CI], 18.2% to 25.0%) of GBS patients and in 3.3% (95% CI, 2.9% to 3.7%) of those in the general population, resulting in a HR of 7.6 (95% CI, 6.2 to 9.3). The highest depression HR was observed within the first 3\u2009months after GBS (HR, 20.5; 95% CI, 13.6 to 30.9). After the first 2\u2009years, GBS patients and the general population members had similar long\u2010term depression risks with an HR of 0.8 (95% CI, 0.6 to 1.2).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>During the first 2\u2009years after GBS hospital admission, patients with GBS had a 7.6\u2010fold increased hazard of depression compared with individuals in the general population. Two years after GBS, the risk of depression was similar to that of the background population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.27816","type":"journal-article","created":{"date-parts":[[2023,3,12]],"date-time":"2023-03-12T04:18:37Z","timestamp":1678594717000},"page":"497-505","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Increased risk of depression after\n                    <scp>Guillain\u2010Barr\u00e9<\/scp>\n                    syndrome"],"prefix":"10.1002","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2210-6020","authenticated-orcid":false,"given":"Lotte Sahin","family":"Levison","sequence":"first","affiliation":[{"name":"Department of Neurology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reimar Wernich","family":"Thomsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology, Department of Clinical Medicine Aarhus University Hospital and Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henning","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Neurology Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,28]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182904fcc"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12087"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5653-x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000047956"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25112"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-014-9930-3"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S91125"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S37587"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S199839"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2020.01.017"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq433"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12096"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2004.09.021"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1191\/0269215505cr918oa"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2012.02.026"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(02)00158-2"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.2.409"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physio.2009.04.001"},{"key":"e_1_2_11_20_1","article-title":"Psychiatric sequelae of Guillain\u2010Barr\u00e9 syndrome: towards a multidisciplinary team approach","volume":"12","author":"Hillyar C","year":"2020","journal-title":"Cureus"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41983-018-0007-1"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2017.08.022"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02906.x"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2009.00243.x"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000011342"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-11-83"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70251-0"},{"key":"e_1_2_11_28_1","unstructured":"Poul Videbech Center for Neuropsychiatric Depression Research and Psychiatric Center Glostrup.https:\/\/pro.medicin.dk\/laegemiddelgrupper\/grupper\/315574. Accessed February 28 2023."},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.02999.x"},{"key":"e_1_2_11_30_1","unstructured":"The Danish Health Data Authority a part of The Ministry of Health.https:\/\/sundhedsdatastyrelsen.dk\/da\/english. Accessed February 28 2023."},{"key":"e_1_2_11_31_1","unstructured":"The Danish Data Protection Agency.https:\/\/www.datatilsynet.dk\/english\/legislation. 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