{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T14:16:37Z","timestamp":1776435397254,"version":"3.51.2"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T00:00:00Z","timestamp":1686528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["pericles.pericles-gcp.literatumonline.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>The reason for the variable rate of progression of patients with carpal tunnel syndrome (CTS) to thenar muscles impairment is not fully understood. The aim of this study was to evaluate the occurrence of ultrasound signs of recurrent motor branch (RMB) neuropathy in patients with CTS and to correlate imaging findings with clinical and electrophysiological data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two cohorts were recruited, one consisting of CTS patients with electrodiagnostic evidence of prolonged median distal motor latency from wrist to thenar eminence and another consisting of sex\u2010 and age\u2010matched healthy controls. Ultrasound reliability of RMB measurement was assessed by the calculation of the interclass correlation coefficient (ICC). Patients were evaluated with electrodiagnostic tests and asked to complete the Boston Carpal Tunnel Questionnaire. The difference between the RMB diameter in patients and controls was analyzed using a <jats:italic>t<\/jats:italic> test. Correlations between RMB diameter and other parameters were assessed using linear mixed models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>46 hands from 32 patients with CTS and 50 hands from 50 controls were evaluated. The intra\u2010 and interobserver agreements in RMB measurement were very good (ICC\u2009=\u20090.84; 95% confidence interval [CI], 0.75 to 0.90) and good (ICC\u2009=\u20090.79; 95% CI, 0.69 to 0.87). The RMB diameter was significantly larger in patients than in controls (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.0001). No significant correlation was found between the RMB diameter and other variables, except for BMI and median nerve cross\u2010sectional area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Ultrasound is reliable in identifying the RMB and characterizing its abnormalities. In this patient cohort, ultrasound allowed for detection of definite signs of RMB compression neuropathy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27915","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T07:20:06Z","timestamp":1686554406000},"page":"184-190","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Recurrent motor branch neuropathy in carpal tunnel syndrome: An ultrasound study"],"prefix":"10.1002","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7450-6528","authenticated-orcid":false,"given":"Riccardo","family":"Picasso","sequence":"first","affiliation":[{"name":"IRCCS Ospedale Policlinico San Martino  Genoa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Zaottini","sequence":"additional","affiliation":[{"name":"IRCCS Ospedale Policlinico San Martino  Genoa 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hand","volume":"189","author":"Ajmani ML","year":"1996","journal-title":"J Anat."},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20067"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1754-9493-8-8"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11552-006-9006-2"},{"key":"e_1_2_11_7_1","first-page":"326","article-title":"Isolated neuropathy of the recurrent motor branch of the median nerve","volume":"11","author":"Shams OE","year":"2006","journal-title":"Neurosciences."},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1726-4901(09)70068-1"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhsu.2001.24146"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197052020-00007"},{"key":"e_1_2_11_11_1","first-page":"222","article-title":"Transligamentous motor branch of the median nerve discovered during endoscopically assisted carpal tunnel 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