{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T02:12:22Z","timestamp":1790993542603,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:00:00Z","timestamp":1689292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>The aim in this study is to describe the clinical and electrophysiological patterns of pregnancy\u2010related carpal tunnel syndrome (PRCTS) occurring during pregnancy or after delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinical, epidemiological, and electrodiagnostic (EDx) data were studied in 130 women with PRCTS onset during pregnancy (<jats:italic>n<\/jats:italic>\u2009=\u200980) or after delivery (<jats:italic>n<\/jats:italic>\u2009=\u200950). Twenty\u2010six women with PRCTS underwent EDx analysis during pregnancy and 104 after delivery (83 within 6\u2009months of delivery and 21 up to 24\u2009months after pregnancy onset). PRCTS was compared with idiopathic CTS in a control group consisting of 57 age\u2010matched women with 98 cases of CTS. Twenty\u2010four women with PRCTS had clinical and electrophysiological follow\u2010up after corticosteroid injection (CSI) at the wrist.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clinical analysis showed a higher rate of bilateral and diurnal\/permanent paraesthesia and more severe symptoms in PRCTS compared with idiopathic CTS. EDx analysis showed more severe abnormalities in classical tests and a higher rate of conduction block (CB) in PRCTS. Statistical analysis showed a strong negative correlation between the incidence and importance of CB and the time interval at which PRCTS women underwent EDx examination, between pregnancy onset and 24\u2009months later. CSI resulted in significant clinical and EDx improvement in 22 of 24 PRCTS women, with disappearance of all motor and most sensory CBs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>The EDx pattern of PRCTS is an acute\/subacute median nerve lesion at the wrist identified by many CBs. This occurs concurrently with hormonal changes, is responsible for more severe clinical symptoms and EDx data, and it explains why CSI is so effective.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27929","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T11:24:20Z","timestamp":1689333860000},"page":"380-387","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Conduction blocks of the median nerve at the wrist in pregnancy and postpartum carpal tunnel syndromes"],"prefix":"10.1002","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3458-8477","authenticated-orcid":false,"given":"Paul","family":"Seror","sequence":"first","affiliation":[{"name":"Laboratoire d'Electroneuromyographie  Paris France"},{"name":"Laboratoire d'Electroneuromyographie H\u00f4pital de l'Est Parisien, Ramsay GS  Aulnay\/s Bois France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(57)90278-8"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(67)90562-5"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/2277-9175.100143"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-7681(98)80232-5"},{"key":"e_1_2_7_6_1","first-page":"259","article-title":"Long term follow\u2010up of carpal tunnel syndrome during pregnancy: a cohort study and review of the literature","volume":"47","author":"Mondelli M","year":"2007","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(98)90276-3"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(01)00637-X"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(95)00335-Y"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0266-7681_90_90057-B"},{"key":"e_1_2_7_11_1","first-page":"687","article-title":"Severe carpal tunnel syndrome during pregnancy","volume":"22","author":"Seror P","year":"1993","journal-title":"Presse Med"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.5.933"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880180505"},{"key":"e_1_2_7_14_1","first-page":"545","article-title":"Electrodiagnostic characteristics of acute carpal tunnel syndrome","volume":"68","author":"Gordon C","year":"1987","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4260.237"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002060-198806000-00005"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000142535.24626.90"},{"key":"e_1_2_7_18_1","first-page":"194","article-title":"Lesions of the carpal Teno\u2010synovial sheaths in the carpal tunnel syndrome. 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