{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:12:25Z","timestamp":1788790345369,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T00:00:00Z","timestamp":1691107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>Patients with amyotrophic lateral sclerosis (ALS) inevitably visit the emergency department (ED) due to their increased risk of respiratory failure and mobility limitations. However, nationwide data on ED visits by patients with ALS are limited. This study investigated the characteristics of patients with ALS\u2010related ED visits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a cross\u2010sectional study from 2016 to 2020, utilizing a nationwide ED database. The total number of patients with ALS who visited the ED and their primary reasons for visiting\/diagnoses were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 6036 visits to the ED were made by patients with ALS. Of these, 41.8% arrived by ambulance and 27.7% spent &gt;9\u2009h in the ED. Following ED treatment, 57.4% were hospitalized, including 19.3% admitted to the intensive care unit (ICU) and 5.4% who died in the hospital. The primary reasons for ALS\u2010related ED visits were dyspnea (35.2%), feeding tube problems (10.1%), fever (7.8%), and mental status changes (3.6%). The most common diagnoses were pneumonia (14.5%), respiratory failure (5.7%), dyspnea (5.5%), aspiration pneumonia (4.3%), and tracheostomy complications (3.4%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Reasons for ED visits for patients with ALS include acute respiratory distress, as well as concerns related to tube feeding and tracheostomy. To reduce the risk of patients with ALS requiring ED visits, it is essential to ensure the provision of timely respiratory support and high\u2010quality home\u2010based medical care teams that can support and address patients before their condition deteriorates.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27952","type":"journal-article","created":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T13:20:19Z","timestamp":1691155219000},"page":"451-459","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Epidemiology and characteristics of emergency department utilization by patients with amyotrophic lateral sclerosis in <scp>Korea<\/scp> from 2016 to 2020: A nationwide study"],"prefix":"10.1002","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5211-6484","authenticated-orcid":false,"given":"Jung\u2010In","family":"Ko","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, National Medical Center  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6444-977X","authenticated-orcid":false,"given":"Seok\u2010Jin","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Neurology Seoul National University Hospital  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7473-1082","authenticated-orcid":false,"given":"Shin Hye","family":"Yoo","sequence":"additional","affiliation":[{"name":"Center for Palliative Care and Clinical Ethics Seoul National University Hospital  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9558-689X","authenticated-orcid":false,"given":"Belong","family":"Cho","sequence":"additional","affiliation":[{"name":"Public Healthcare Center Seoul National University Hospital  Seoul Republic of Korea"},{"name":"Department of Human Systems Medicine Seoul National University College of Medicine &amp; Hospital  Seoul Republic of Korea"},{"name":"Institute on Aging, Seoul National University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5323-9857","authenticated-orcid":false,"given":"Min Sun","family":"Kim","sequence":"additional","affiliation":[{"name":"Public Healthcare Center Seoul National University Hospital  Seoul Republic of Korea"},{"name":"Department of Pediatrics Seoul National University College of Medicine &amp; Hospital  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9954-6422","authenticated-orcid":false,"given":"Kyae Hyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Public Healthcare Center Seoul National University Hospital  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1626-2721","authenticated-orcid":false,"given":"Sun Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Public Healthcare Center Seoul National University Hospital  Seoul Republic of Korea"},{"name":"Department of Medicine Seoul National University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,8,4]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00754-2018"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.6.753"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0223772"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/09059180.06.00009801"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-40206-4"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ienj.2015.07.004"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/emermed-2015-205473"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2012.05.042"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.2017.028191"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.01.045"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-015-0810-7"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2005.083402"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181bc01a4"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03501.x"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2019.05.011"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-01571-1"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2015.06.012"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2021.36.e121"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2019.60.8.796"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2018.12.023"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30623-7"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/21678421.2022.2035765"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2018-318974"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.74.suppl_4.iv32"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-98990-x"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2019-322213"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2012.8.4.293"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.27952","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T10:26:52Z","timestamp":1706178412000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.27952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,4]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1002\/mus.27952"],"URL":"https:\/\/doi.org\/10.1002\/mus.27952","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,4]]},"assertion":[{"value":"2023-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}