{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T04:39:50Z","timestamp":1794026390833,"version":"4.8.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction\/Aims<\/jats:title>\n                    <jats:p>Hourglass\u2010like constrictions (HGCs) of involved nerves in neuralgic amyotrophy (NA) (Parsonage\u2013Turner syndrome) have been increasingly recognized with magnetic resonance neurography (MRN). This study sought to determine the sensitivity of HGCs, detected by MRN, among electromyography (EMG)\u2010confirmed NA cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study retrospectively reviewed records of patients with the clinical diagnosis of NA, and with EMG confirmation, who underwent 3\u2010Tesla MRN within 90\u2009days of EMG at a single tertiary referral center between 2011 and 2021. \u201cSevere NA\u201d positive cases were defined by a clinical diagnosis and specific EMG criteria: fibrillation potentials or positive sharp waves, along with motor unit recruitment (MUR) grades of \u201cdiscrete\u201d or \u201cnone.\u201d On MRN, one or more HGCs, defined as focally decreased nerve caliber or diffusely beaded appearance, was considered \u201cimaging\u2010positive.\u201d Post hoc inter\u2010rater reliability for HGCs was measured by comparing the original MRN report against subsequent blinded interpretation by a second radiologist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 123 NA patients with 3\u2010Tesla MRN performed within 90\u2009days of EMG were identified. HGCs were observed in 90.2% of all NA patients. In \u201csevere NA\u201d cases, based on the above EMG criteria, HGC detection resulted in a sensitivity of 91.9%. Nerve\u2010by\u2010nerve analysis (183 nerve\u2010muscle pairs, nerves assessed by MRN, muscles assessed by EMG) showed a sensitivity of 91.0%. The second radiologist largely agreed with the original HGC evaluation, (94.3% by subjects, 91.8% by nerves), with no significant difference between evaluations (subjects:\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20092.27,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.132, nerves:\n                      <jats:italic>\u03c7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.98,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.323).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>MRN detection of HGCs is common in NA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.27961","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T07:20:38Z","timestamp":1692775238000},"page":"42-51","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Hourglass\u2010like constrictions on\n                    <scp>MRI<\/scp>\n                    are common in electromyography\u2010confirmed cases of neuralgic amyotrophy (\n                    <scp>Parsonage\u2013Turner<\/scp>\n                    syndrome): A tertiary referral center experience"],"prefix":"10.1002","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9105-5415","authenticated-orcid":false,"given":"Darryl B.","family":"Sneag","sequence":"first","affiliation":[{"name":"Department of Radiology and Imaging Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey","family":"Urban","sequence":"additional","affiliation":[{"name":"Hand and Upper Extremity Service, Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim Y.","family":"Li","sequence":"additional","affiliation":[{"name":"Weill Cornell Medical College  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8869-9992","authenticated-orcid":false,"given":"Philip G.","family":"Colucci","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily G.","family":"Pedrick","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6956-1090","authenticated-orcid":false,"given":"Clare A.","family":"Nimura","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph H.","family":"Feinberg","sequence":"additional","affiliation":[{"name":"Department of Physiatry Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo J.","family":"Milani","sequence":"additional","affiliation":[{"name":"Department of Physiatry Hospital for Special Surgery  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2847-9378","authenticated-orcid":false,"given":"Ek T.","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging 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