{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T03:55:01Z","timestamp":1776916501515,"version":"3.51.2"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T00:00:00Z","timestamp":1697241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009905","name":"FLS Industries A\/S Gavefond","doi-asserted-by":"publisher","award":["200009121"],"award-info":[{"award-number":["200009121"]}],"id":[{"id":"10.13039\/501100009905","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Telerehabilitation provides physical training to patients through telecommunication networks. We examined the feasibility, safety, and efficacy of an integrated, personalized, respiratory and motor telerehabilitation program for pediatric patients with hereditary neuromuscular disorders (NMDs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Stable pediatric patients were recruited for a 16\u2010week home training program with personalized pulmonary, upper and lower limb exercises. Patients reviewed instructional videos at home and attended bi\u2010weekly follow\u2010ups through video or audio calls, text messages, or emails. The primary outcomes were respiratory function, Medical Research Council (MRC) grading, hand\/pinch strength, 6\u2010minute walk test, and Pediatric Quality\u2010of\u2010Life Inventory 3.0 Neuromuscular Module survey. The secondary outcomes were study compliance and user feedback.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with spinal muscular atrophy (<jats:italic>n<\/jats:italic>\u2009=\u20094), congenital myasthenic syndrome (<jats:italic>n<\/jats:italic>\u2009=\u20092), and Duchenne muscular dystrophy (<jats:italic>n<\/jats:italic>\u2009=\u20092) completed the program. The median weekly exercise time was 101.3\u2009min (range: 30.0\u2013266.9). No extra face\u2010to\u2010face physiotherapy sessions were requested by the patients. No adverse events were reported. After the study, patients showed improvements in maximal expiratory pressure (35.0 vs. 47.5\u2009cm H2O, <jats:italic>p<\/jats:italic>\u2009=\u2009.028) and maintained their MRC grade, hand\/pinch strength, and walking distance. Patients also reported improvements in the Pediatric Quality\u2010of\u2010Life Inventory 3.0 Neuromuscular Module survey score (74.5 vs. 87.0, <jats:italic>p<\/jats:italic>\u2009=\u2009.036). Patients rated the overall program highly (mean: 4.00\/5.00) and recommended it as a standard of care (mean: 4.38\/5.00).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Our telerehabilitation program was feasible, safe, and possibly effective for this pilot cohort of stable pediatric patients with hereditary NMDs. Larger\u2010scale studies for longer periods are warranted to confirm the results.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27982","type":"journal-article","created":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T09:03:20Z","timestamp":1697274200000},"page":"857-864","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A pilot study of an integrated, personalized, respiratory and\u00a0motor telerehabilitation program for pediatric patients with hereditary neuromuscular disorders"],"prefix":"10.1002","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-7287-5654","authenticated-orcid":false,"given":"Michael Kwan Leung","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine The University of Hong Kong  Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice Yuen Yee","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy The Duchess of Kent Children's Hospital at Sandy Bay  Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuk Kuen","family":"Chau","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine The University of Hong Kong  Hong Kong"},{"name":"Department of Paediatrics and Adolescent Medicine The Duchess of Kent Children's Hospital at Sandy Bay  Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5292-5510","authenticated-orcid":false,"given":"Jaime S","family":"Rosa Duque","sequence":"additional","affiliation":[{"name":"Department of Paediatrics and Adolescent Medicine The University of Hong Kong  Hong Kong"},{"name":"Department of Paediatrics and Adolescent Medicine The Duchess of Kent Children's Hospital at Sandy Bay  Hong 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