{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:24:26Z","timestamp":1792153466271,"version":"4.4.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T00:00:00Z","timestamp":1699401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>Femoral neuropathies can cause severe, prolonged debility, yet there have been few clinical and electrodiagnostic (EDx) studies addressing this condition. The aim of this study was to better understand the etiologies, EDx features, and clinical course of femoral neuropathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We identified patients evaluated at Mayo Clinic Rochester between January 1, 1999 and July 31, 2019, with possible new femoral neuropathy ascertained via International Classification of Diseases\u2010versions 9 and 10 diagnosis codes presenting within 6\u2009months of symptom onset.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A retrospective review of 1084 records was performed and we ultimately identified 159 patients with isolated femoral neuropathy for inclusion. The most common femoral neuropathy etiologies were compressive (40%), perioperative stretch (35%), and inflammatory (6%). Presenting symptoms included weakness (96%), sensory loss (73%), and pain (53%). Presenting motor physical exam findings demonstrated moderate weakness (34%) or no activation (25%) of knee extension and mild (32%) or moderate (35%) weakness of hip flexion. Seventy\u2010two percent of patients underwent EDx testing, including 22 with femoral motor nerve conduction studies. Treatment often involved physical therapy (89%) and was otherwise etiology\u2010specific. In patients with follow\u2010up data available (<jats:italic>n<\/jats:italic> =\u2009154), 83% had subjective clinical improvement at follow\u2010up with a mean time to initial improvement of 3.3\u2009months and mean time to recovery at final follow\u2010up of 14.8\u2009months. Only 48% of patients had nearly complete or complete recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>In our cohort, the most common etiologies of femoral neuropathy were compression or perioperative stretch with high initial morbidity. Although motor recovery is common, improvement is often prolonged and incomplete.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.27994","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T09:08:45Z","timestamp":1699520925000},"page":"64-71","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Femoral neuropathy: A clinical and electrodiagnostic review"],"prefix":"10.1002","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5708-7109","authenticated-orcid":false,"given":"Ashley R.","family":"Santilli","sequence":"first","affiliation":[{"name":"Department of Neurology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Martinez\u2010Thompson","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott J. A.","family":"Speelziek","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6760-3859","authenticated-orcid":false,"given":"Nathan P.","family":"Staff","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1884-5824","authenticated-orcid":false,"given":"Ruple S.","family":"Laughlin","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,8]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"459","volume-title":"Electromyography and Neuromuscular Disorders","author":"Preston DC","year":"2021"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2018.2955"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jhps\/hny050"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.6.1197"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.31.10.1327"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007020"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2012.08.014"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.9.2113"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000367"},{"key":"e_1_2_10_11_1","first-page":"141","article-title":"Meralgia paresthetica and the lateral femoral cutaneous nerve","volume":"7","author":"Solnizky O","year":"1954","journal-title":"Bulletin."},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20868"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1988.10.3.85"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10016-006-9059-2"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-3804(96)80112-5"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199407000-00004"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/CND.0b013e3181f3dbe7"},{"key":"e_1_2_10_18_1","first-page":"90","article-title":"Femoral neuropathy after vaginal surgery: a complication of the lithotomy position","volume":"31","author":"Wilson M","year":"2011","journal-title":"Gynaecol Case Rep"},{"key":"e_1_2_10_19_1","first-page":"306","article-title":"Femoral neuropathy: a complication of the lithotomy position","volume":"17","author":"Gombar KK","year":"1992","journal-title":"Reg Anesth."},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880170416"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjy171"},{"key":"e_1_2_10_22_1","first-page":"145","article-title":"Femoral neuropathy following total hip arthroplasty: review and management guidelines","volume":"78","author":"Fox AJS","year":"2012","journal-title":"Acta Orthop Belg"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0883-5403(08)80057-5"},{"key":"e_1_2_10_24_1","first-page":"516","article-title":"Iatrogenic femoral neuropathy subsequent to abdominal hysterectomy: incidence and prevention","volume":"60","author":"Kvist\u2010Poulsen H","year":"1982","journal-title":"Obstet Gynecol"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2015.12.072"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22334"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26473"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2013.10.027"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq252"},{"key":"e_1_2_10_30_1","first-page":"311","article-title":"Perioperative nerve injury after total knee arthroplasty: regional anesthesia risk during a 20\u2010year cohort study","volume":"144","author":"Jacob AK","year":"2011","journal-title":"Perioper Med."}],"updated-by":[{"DOI":"10.1002\/mus.28055","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T00:00:00Z","timestamp":1707436800000}}],"container-title":["Muscle &amp; 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