{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:22:38Z","timestamp":1772994158079,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction\/Aims<\/jats:title>\n                    <jats:p>Type 1 myotonic dystrophy (DM1) is a neuromuscular disorder of multiple organ systems with important electrophysiologic (EP) manifestations, leading to a cumulative incidence of sudden death of 6.6%. Due to genetic anticipation, there is a pediatric subset of this patient population. However, most EP research on DM1 patients has been in adults, making cardiac care for pediatric patients difficult and directed by adult guidelines which often leads to cardiovascular implantable electronic device (CIED) implants. We sought to investigate the prevalence of CIEDs in the pediatric DM1 population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Vizient\u00ae Clinical Data Base was queried from October 2019 to October 2023 for admissions with and without ICD\u201010 code for myotonic dystrophy (G71.11), with and without codes for presence of a pacemaker or ICD (Z95.0, Z95.810). Patients who were identified were stratified by age: Pediatric (0\u201321\u2009years) and Adult (22\u201350\u2009years).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Prevalence of CIED in pediatric DM1 was 2.1% and in adult DM1 was 15.8%. When comparing to pediatric and adult patients with CIED and without DM1, the odds ratio for CIED in pediatric DM1 was 48.8, compared to 23.3 for CIED in adult DM1.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>There are pediatric DM1 patients who have received CIED despite a lack of data to inform this decision\u2010making. Further research will be important to ensure appropriate use of CIED in this population and to develop appropriate guidelines to direct management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.28188","type":"journal-article","created":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T02:14:15Z","timestamp":1719627255000},"page":"1077-1081","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of cardiovascular implantable electronic devices in children with type 1 myotonic dystrophy"],"prefix":"10.1002","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1196-0974","authenticated-orcid":false,"given":"Omar","family":"Meziab","sequence":"first","affiliation":[{"name":"Department of Pediatrics (Cardiology) University of Arizona  Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9013-5723","authenticated-orcid":false,"given":"Michael D.","family":"Seckeler","sequence":"additional","affiliation":[{"name":"Department of Pediatrics (Cardiology) University of Arizona  Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Scherer","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Arizona  Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent J.","family":"Barber","sequence":"additional","affiliation":[{"name":"Department of Pediatrics (Cardiology) University of Arizona  Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.214197"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062800"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.11.028"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2012.03351.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.08.037"},{"issue":"10","key":"e_1_2_9_7_1","first-page":"751","article-title":"Incidence and predictors of sudden death, major conduction defects and sustained ventricular tachyarrhythmias in 1388 patients with myotonic dystrophy type 1","volume":"38","author":"Wahbi K","year":"2017","journal-title":"Eur Heart J"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.346"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.03.069"},{"key":"e_1_2_9_10_1","first-page":"1038","article-title":"A Normal electrocardiogram does not exclude infra\u2010Hisian conduction disease in patients with myotonic dystrophy type 1","volume":"7","author":"Creta A","year":"2021","journal-title":"J Am Coll Cardiol EP"},{"key":"e_1_2_9_11_1","first-page":"1049","article-title":"Electrophysiologic consequences and sudden death in myotonic dystrophy","volume":"7","author":"Etheridge SP","year":"2021","journal-title":"J Am Coll Cardiol EP"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000526"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab364"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.10.043"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.07.038"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000144343.91136.CF"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.910660"},{"key":"e_1_2_9_18_1","unstructured":"Vizient\u00ae Clinical Data Base.www.vizientinc.com. 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