{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T09:13:23Z","timestamp":1784279603438,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T00:00:00Z","timestamp":1719360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>T2 magnetic resonance imaging (MRI) mapping has been applied to carpal tunnel syndrome (CTS) for quantitative assessment of the median nerve. However, quantitative changes in the median nerve before and after surgery using T2 MRI mapping remain unclear. We aimed to investigate whether pathological changes could be identified by pre\u2010 and postoperative T2 MRI mapping of the median nerve in CTS patients after open carpal tunnel release.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective study that measured median nerve T2 and cross\u2010sectional area (CSA) values at the distal carpal tunnel, hamate bone, proximal carpal tunnel, and forearm levels pre\u2010 and postoperatively. Associations between T2, CSA, and nerve conduction latency were also evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 36 patients with CTS (mean age, 64.5\u2009\u00b1\u200911.7\u2009years) who underwent surgery were studied. The mean preoperative T2 values significantly decreased from 56.3 to 46.9\u2009ms at the proximal carpal tunnel levels (<jats:italic>p<\/jats:italic>\u2009=\u2009.001), and from 52.4 to 48.7\u2009ms at the hamate levels postoperatively (<jats:italic>p<\/jats:italic>\u2009=\u2009.04). Although there was a moderate association between preoperative T2 values at the distal carpal tunnel levels and distal motor latency values (<jats:italic>r<\/jats:italic>\u2009=\u2009\u2212.46), other T2 values at all four carpal tunnel levels were not significantly associated with CSA or nerve conduction latency pre\u2010 or postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>T2 MRI mapping of the carpal tunnel suggested a decrease in nerve edema after surgery. T2 MRI mapping provides quantitative information on the median nerve before and after surgery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.28191","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T13:14:04Z","timestamp":1719407644000},"page":"346-351","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["<scp>T2<\/scp> magnetic resonance imaging mapping and morphology of the median nerve before and after surgery in carpal tunnel syndrome"],"prefix":"10.1002","volume":"70","author":[{"given":"Harunori","family":"Kondo","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Fujita Health University  Toyoake Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2312-3540","authenticated-orcid":false,"given":"Taku","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiko","family":"Hayakawa","sequence":"additional","affiliation":[{"name":"Aiko Orthopedic Surgery Hospital  Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Maeda","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Fujita Health University  Toyoake Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Funahashi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Fujita Health University  Toyoake Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kuroiwa","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Fujita Health University  Toyoake Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Kawano","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Fujita Health University  Toyoake Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuji","family":"Iwamoto","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Fujita Health University  Toyoake Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2010.06.010"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753193420948406"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3171\/JNS\/2008\/108\/3\/0541"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2002.96.6.1046"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-015-3052-8"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.20.23066"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nic.2004.02.002"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-006-0180-y"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-021-08447-y"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.26615"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-019-06091-1"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-014-1852-3"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24448"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000000265"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.27205"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.16.00719"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61517-8"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.39.7.615"},{"issue":"4","key":"e_1_2_10_20_1","first-page":"973","article-title":"Imaging of intraneural edema by using gadolinium\u2010enhanced MR imaging: experimental compression injury","volume":"26","author":"Kobayashi S","year":"2005","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2016.09.011"}],"container-title":["Muscle &amp; 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