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A robust, high\u2010resolution, heavily T2\u2010weighted fluid\u2010sensitive sequence performed on a 3.0 Tesla magnet system remains the main workhorse MRN sequence. In specific clinical scenarios, adjunct techniques such as diffusion\u2010weighted imaging can be added to a protocol for disease characterization. In addition, gadolinium\u2010based contrast material can also be administered for the purposes of image optimization (suppress adjacent vascular signal) and disease characterization. Technical modifications to field of view and planes of imaging can be made based on the clinical question and discussion with the radiologist(s). On fluid\u2010sensitive MRN sequences, a normal peripheral nerve exhibits iso\u2010 to minimally hyperintense signal relative to skeletal muscle with a predictable trajectory, preserved \u201cfascicular\u201d architecture, and tapered caliber from proximal to distal. Peripheral nerve abnormalities on MRN include alterations in signal, caliber, architecture, diffusion characteristics as well as enhancement and provide information regarding the underlying etiology. Although some MRN findings including nerve hyperintensity and long\u2010segmental enlargement are nonspecific, there are certain diagnoses that can be made with high certainty based on imaging including benign peripheral nerve tumors, high\u2010grade peripheral nerve injury, and intraneural ganglia. The purpose of this article is to familiarize a neuromuscular clinician with fundamentals of MRN acquisition and interpretation to facilitate communication with the neuromuscular radiologist and optimize patient care.<\/jats:p>","DOI":"10.1002\/mus.28283","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T09:39:06Z","timestamp":1730367546000},"page":"293-308","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A neuromuscular clinician's guide to magnetic resonance neurography"],"prefix":"10.1002","volume":"71","author":[{"given":"Jenifer","family":"Pitman","sequence":"first","affiliation":[{"name":"Musculoskeletal Imaging Division, The Russell H. 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