{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T07:40:10Z","timestamp":1749109210723,"version":"3.41.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T00:00:00Z","timestamp":1743638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction\/Aims<\/jats:title><jats:p>Accurate measurement of knee\u2010extensor strength in people with inclusion body myositis (IBM) is vital to track disease progression and provide a standardized outcome for clinical trials. Isokinetic dynamometers are the current gold standard tool for measuring knee\u2010extensor strength. A less costly, more portable tool would have more widespread clinical and research applications. Current practice is to use handheld dynamometry, but there are concerns around the accuracy of this method as it relies on precise operator technique. This study investigates whether stabilization of the handheld dynamometer with a strap (SSHD) improves agreement with the isokinetic dynamometer (IKD) for measurement of knee\u2010extensor strength in IBM participants compared to operator\u2010stabilized handheld dynamometry (OSHD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifteen IBM participants had bilateral knee\u2010extensor force measured using three methods of dynamometry on the same day: the isokinetic dynamometer, operator\u2010stabilized handheld dynamometry, and strap\u2010stabilized handheld dynamometry. A crossover design was used to account for fatigue bias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Intraclass correlations (ICC) indicated poor absolute agreement of the IKD with OSHD (Strong leg\u2009=\u20090.240, Weak leg\u2009=\u20090.328), which was better for the SSHD method. Using the SSHD reduced the bias (i.e., there was less underestimation of force) between SSHD and the IKD compared to OSHD and the IKD (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05), indicating that strap\u2010stabilized handheld dynamometry improved agreement and intraclass correlations with the IKD compared with operator\u2010stabilized dynamometry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Strap\u2010stabilized handheld dynamometry of knee extensor strength is feasible in IBM patients and may correlate better with isokinetic dynamometry than operator\u2010stabilized handheld dynamometry, but larger studies are needed to confirm this finding.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.28406","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T22:37:00Z","timestamp":1743806220000},"page":"42-48","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Strapped for Strength: A Comparison Study of Dynamometry Techniques to Evaluate Knee Extensor Strength in Inclusion Body Myositis"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9501-2306","authenticated-orcid":false,"given":"Katie","family":"Sch\u00fctze","sequence":"first","affiliation":[{"name":"School of Medicine The University of Notre Dame Australia  Fremantle Western Australia Australia"},{"name":"Sir Charles Gairdner Hospital  Nedlands Western Australia Australia"},{"name":"Perron Institute for Neurological and Translational Science  Nedlands Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Cooper","sequence":"additional","affiliation":[{"name":"Perron Institute for Neurological and Translational Science  Nedlands Western Australia Australia"},{"name":"Centre for Molecular Medicine &amp; Innovative Therapeutics Murdoch University  Murdoch Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brook","family":"Galna","sequence":"additional","affiliation":[{"name":"Centre for Molecular Medicine &amp; Innovative Therapeutics Murdoch University  Murdoch Western Australia Australia"},{"name":"Centre for Healthy Ageing Murdoch University  Murdoch Western Australia Australia"},{"name":"School of Allied Health (Exercise Science) Murdoch University  Murdoch Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"Beer","sequence":"additional","affiliation":[{"name":"Perron Institute for Neurological and Translational Science  Nedlands Western Australia Australia"},{"name":"Centre for Molecular Medicine &amp; Innovative Therapeutics Murdoch University  Murdoch Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Fairchild","sequence":"additional","affiliation":[{"name":"Centre for Molecular Medicine &amp; Innovative Therapeutics Murdoch University  Murdoch Western Australia Australia"},{"name":"Centre for Healthy Ageing Murdoch University  Murdoch Western Australia Australia"},{"name":"School of Allied Health (Exercise Science) Murdoch University  Murdoch Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madeline","family":"Schopp","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Notre Dame Australia  Fremantle Western Australia Australia"},{"name":"Western Australian Country Health Service  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Brusch","sequence":"additional","affiliation":[{"name":"Perron Institute for Neurological and Translational Science  Nedlands Western Australia Australia"},{"name":"Department of Immunology, Sir Charles Gairdner Hospital  Nedlands Western Australia Australia"},{"name":"School of Medicine The University of Western Australia  Claremont Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6591-1444","authenticated-orcid":false,"given":"Merrilee","family":"Needham","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Notre Dame Australia  Fremantle Western Australia Australia"},{"name":"Perron Institute for Neurological and Translational Science  Nedlands Western Australia Australia"},{"name":"Centre for Molecular Medicine &amp; Innovative Therapeutics Murdoch University  Murdoch Western Australia Australia"},{"name":"School of Medicine The University of Western Australia  Claremont Western Australia Australia"},{"name":"Department of Neurology, Fiona Stanley Hospital  Murdoch Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,3]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_11_2_1","DOI":"10.1038\/s41584-019-0186-x"},{"doi-asserted-by":"publisher","key":"e_1_2_11_3_1","DOI":"10.1212\/WNL.0000000000000642"},{"doi-asserted-by":"publisher","key":"e_1_2_11_4_1","DOI":"10.1016\/S2665-9913(20)30280-0"},{"doi-asserted-by":"publisher","key":"e_1_2_11_5_1","DOI":"10.1016\/S2665-9913(20)30346-5"},{"doi-asserted-by":"publisher","key":"e_1_2_11_6_1","DOI":"10.1016\/S1474-4422(23)00275-2"},{"doi-asserted-by":"publisher","key":"e_1_2_11_7_1","DOI":"10.1007\/s00415-023-11878-w"},{"doi-asserted-by":"publisher","key":"e_1_2_11_8_1","DOI":"10.1002\/mus.22321"},{"doi-asserted-by":"publisher","key":"e_1_2_11_9_1","DOI":"10.1002\/mus.25603"},{"doi-asserted-by":"publisher","key":"e_1_2_11_10_1","DOI":"10.1016\/j.nmd.2012.05.004"},{"doi-asserted-by":"publisher","key":"e_1_2_11_11_1","DOI":"10.1002\/mus.26859"},{"doi-asserted-by":"publisher","key":"e_1_2_11_12_1","DOI":"10.1016\/j.pmrj.2010.10.025"},{"doi-asserted-by":"publisher","key":"e_1_2_11_13_1","DOI":"10.1519\/JSC.0000000000002982"},{"doi-asserted-by":"publisher","key":"e_1_2_11_14_1","DOI":"10.1007\/BF02519999"},{"doi-asserted-by":"publisher","key":"e_1_2_11_15_1","DOI":"10.2519\/jospt.1991.13.4.191"},{"doi-asserted-by":"publisher","key":"e_1_2_11_16_1","DOI":"10.1519\/JSC.0b013e3181e4f5ce"},{"unstructured":"International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use \u201cIntegrated Addendum to ICH E6(R1): Guideline for Good Clinical Practice E6(R2) \u201d2016.","key":"e_1_2_11_17_1"},{"volume-title":"Muscles, Testing and Function","year":"1993","author":"Kendall F. P.","key":"e_1_2_11_18_1"},{"doi-asserted-by":"publisher","key":"e_1_2_11_19_1","DOI":"10.11613\/BM.2015.015"},{"doi-asserted-by":"publisher","key":"e_1_2_11_20_1","DOI":"10.1016\/j.jcm.2016.02.012"},{"doi-asserted-by":"publisher","key":"e_1_2_11_21_1","DOI":"10.1016\/j.nmd.2013.08.007"},{"doi-asserted-by":"publisher","key":"e_1_2_11_22_1","DOI":"10.1519\/JSC.0b013e3181aa36b8"},{"doi-asserted-by":"publisher","key":"e_1_2_11_23_1","DOI":"10.1159\/000091824"},{"volume-title":"Introduction to Measurement Theory","year":"1979","author":"Allen M. J.","key":"e_1_2_11_24_1"},{"doi-asserted-by":"publisher","key":"e_1_2_11_25_1","DOI":"10.1371\/journal.pone.0194531"},{"doi-asserted-by":"publisher","key":"e_1_2_11_26_1","DOI":"10.3233\/BMR-170829"},{"doi-asserted-by":"publisher","key":"e_1_2_11_27_1","DOI":"10.1186\/s13104-018-3128-9"},{"doi-asserted-by":"publisher","key":"e_1_2_11_28_1","DOI":"10.1016\/j.jsams.2012.01.003"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.28406","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T07:19:00Z","timestamp":1749107940000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.28406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,3]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/mus.28406"],"URL":"https:\/\/doi.org\/10.1002\/mus.28406","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"type":"print","value":"0148-639X"},{"type":"electronic","value":"1097-4598"}],"subject":[],"published":{"date-parts":[[2025,4,3]]},"assertion":[{"value":"2024-10-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}