{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:19:20Z","timestamp":1791389960782,"version":"4.3.3"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100003157","name":"Myasthenia Gravis Foundation of America","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100003157","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction\/Aims<\/jats:title>\n                    <jats:p>Myasthenia gravis (MG) specific outcome measures are being used in clinical trials to evaluate therapeutic effectiveness. These validated tools are also becoming a necessity in clinical practice, with payors in the US market often requiring them to be used to monitor disease state. There is considerable variation and subjectivity regarding their use. This study aimed to develop consensus\u2010based recommendations for the standardization of MG specific outcome measures in clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A panel of 10\u2009US\u2010based MG specialists developed consensus\u2010based recommendations based on three rounds of formal voting using the UCLA\u2010RAND appropriateness method after surveying myasthenia gravis clinicians and developing a focus group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty one expert consensus statements based on six themes were developed following clinician survey result review and focus group theme development. Some key recommendations include: the MGFA Clinical Classification assesses disease at that examination and should be updated at intervals of 3\u20136\u2009months to reflect current clinical status. MGFA PIS represents the overall clinical judgment of the evaluator without the requirement for a defined change in scores on any outcome measure. Patient\u2010reported items, such as MG\u2010ADL and MGC, should be referenced to the previous 1\u2009week to optimize recall. Additional recommendations include scoring outcome measures in the presence of co\u2010morbidity, scoring specific physical exam findings, and clarification regarding the administration of outcome measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This method provided expert consensus\u2010based recommendations for the use of MG\u2010specific outcome measures and exam findings to help standardize how they are used in clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.28417","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T04:49:10Z","timestamp":1745297350000},"page":"56-65","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Standardization of Myasthenia Gravis Outcome Measures in Clinical Practice: A Report of the\n                    <scp>MGFA<\/scp>\n                    Task Force"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7234-3254","authenticated-orcid":false,"given":"Katherine","family":"Ruzhansky","sequence":"first","affiliation":[{"name":"Medical University of South Carolina  Charleston SC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4248-8927","authenticated-orcid":false,"given":"Yuebing","family":"Li","sequence":"additional","affiliation":[{"name":"Cleveland Clinic  Cleveland OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil I.","family":"Wolfe","sequence":"additional","affiliation":[{"name":"University at Buffalo State University of New York  Buffalo NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2773-2506","authenticated-orcid":false,"given":"Srikanth","family":"Muppidi","sequence":"additional","affiliation":[{"name":"Stanford University  Stanford CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey T.","family":"Guptill","sequence":"additional","affiliation":[{"name":"Argenx BV, Duke University School of Medicine  Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5034-6988","authenticated-orcid":false,"given":"Michael K.","family":"Hehir","sequence":"additional","affiliation":[{"name":"Larner College of Medicine University of Vermont  Burlington VT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazen M.","family":"Dimachkie","sequence":"additional","affiliation":[{"name":"University of Kansas Medical Center  Kansas City KS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8195-0141","authenticated-orcid":false,"given":"Henry J.","family":"Kaminski","sequence":"additional","affiliation":[{"name":"George Washington University  Washington, D.C 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