{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T14:05:53Z","timestamp":1771164353289,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:00:00Z","timestamp":1768262400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T00:00:00Z","timestamp":1768262400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction\/Aims<\/jats:title>\n                    <jats:p>The hypoglossal nerve is primarily responsible for tongue movement, but studies on its conduction are scarce. The F\u2010wave, generated by antidromic depolarization of spinal motor neurons, serves as an indicator of proximal motor nerve conduction and is commonly used to assess proximal segments, particularly in distal limb nerves. Our aim was to investigate the F\u2010wave of the hypoglossal nerve in healthy subjects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Healthy adult volunteers underwent bilateral hypoglossal nerve F\u2010wave testing. Recordings were obtained from the genioglossus muscles using paired monopolar needle electrodes placed 5\u2009mm from the midline on the internal concave surface of the jaw, adjacent to the mental spines. Superficial stimulation was performed with a bipolar electrical stimulator applied to the hypoglossal nerve in the neck, one fingerbreadth below the middle third of the mandibular body. Compound muscle action potentials (CMAPs) and F\u2010waves were recorded, with 10 to 20 stimuli applied to obtain 10 F\u2010waves, using the shortest response for analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 20 participants with 40 hypoglossal nerves were studied. F\u2010waves were successfully recorded in 39 out of 40 hypoglossal nerves, with a mean latency of 11.19\u2009ms (IQR 8.7\u201320.6; SD 1.7). No significant differences in latency or amplitude were found between sides.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This study found reproducible F\u2010waves, enabling exploration of the proximal segments of the hypoglossal nerve. These findings could be valuable for diagnostic purposes in various pathological conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.70140","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T09:21:07Z","timestamp":1768296067000},"page":"490-494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Motor Nerve Conduction of the Hypoglossal Nerve With F\u2010Waves in Healthy Adults"],"prefix":"10.1002","volume":"73","author":[{"given":"Mariana","family":"Bendersky","sequence":"first","affiliation":[{"name":"Facultad de Medicina Universidad de Buenos Aires  Ciudad Aut\u00f3noma de Buenos Aires Argentina"},{"name":"Hospital J.A. Fern\u00e1ndez  Ciudad Aut\u00f3noma de Buenos Aires Argentina"},{"name":"Finochietto Clinic  Ciudad Aut\u00f3noma de Buenos Aires Argentina"},{"name":"Instituto Argentino de Investigaci\u00f3n Neurol\u00f3gica (IADIN)  Ciudad Aut\u00f3noma de Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5645-5045","authenticated-orcid":false,"given":"Roberto D","family":"Rey","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Universidad de Buenos Aires  Ciudad Aut\u00f3noma de Buenos Aires Argentina"},{"name":"Finochietto Clinic  Ciudad Aut\u00f3noma de Buenos Aires Argentina"},{"name":"Instituto Argentino de Investigaci\u00f3n Neurol\u00f3gica (IADIN)  Ciudad Aut\u00f3noma de Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.5962\/bhl.title.20311"},{"key":"e_1_2_10_3_1","volume-title":"Anatom\u00eda Humana, 11 Ed.: Descriptiva, Topogr\u00e1fica y Funcional: Sistema Nervioso Central, V\u00edas y Centros Nerviosos","author":"Rouvi\u00e8re H.","year":"2005"},{"key":"e_1_2_10_4_1","volume-title":"Cranial Nerves: Function and Dysfunction","author":"Wilson\u2010Pauwels L.","year":"2010"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880110506"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(98)70257-8"},{"issue":"5","key":"e_1_2_10_7_1","first-page":"265","article-title":"Electrophysiological Studies of Nerve and Reflex Activity in Normal Man. I. Identification of Certain Reflexes in the Electromyogram and the Conduction Velocity of Peripheral Nerve Fibers","volume":"86","author":"Magladery J. W.","year":"1950","journal-title":"Bulletin of the Johns Hopkins Hospital"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880151102"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199738687.001.0001"},{"key":"e_1_2_10_10_1","first-page":"89","volume-title":"Neuromuscular Disorders in Clinical Practice","author":"Shapiro B. E.","year":"2013"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awad342"},{"issue":"3","key":"e_1_2_10_12_1","first-page":"167","article-title":"F\u2010Waves of the Facial Muscles in Healthy Control Subjects and in Patients With Peripheral Facial Nerve Disturbance","volume":"39","author":"Ishikawa M.","year":"1999","journal-title":"Electromyography and Clinical Neurophysiology"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.1996.11740368"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNP.0000000000000085"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2017.10.006"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-007-0105-5"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-8467(01)00115-9"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25197"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.10.007"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.70140","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mus.70140","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.70140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T13:41:48Z","timestamp":1771162908000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.70140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,13]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/mus.70140"],"URL":"https:\/\/doi.org\/10.1002\/mus.70140","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,13]]},"assertion":[{"value":"2025-06-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}