{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:05:07Z","timestamp":1791317107576,"version":"4.3.1"},"reference-count":53,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["U01 AR065113\u201001"],"award-info":[{"award-number":["U01 AR065113\u201001"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Motion sensing technology can be utilized to capture detailed upper extremity (UE) motion to reconstruct an individual's three\u2010dimensional (3D) reachable workspace (RWS). The RWS can be quantified as relative surface area (RSA), providing an innovative surrogate measure to assess UE mobility and function. Numerous studies have shown that RSA can reliably distinguish between healthy and impaired UE function and also is able to detect clinically relevant longitudinal changes, with sufficient sensitivity to detect small differences even in slowly\u2010progressive conditions. After more than a decade of experience in clinical studies, RWS has been shown to be a valid, reliable, and sensitive UE clinical outcome assessment (COA) tool, with clinical utility in various neuromuscular diseases in which UE impairment is significant, including facioscapulohumeral dystrophy (FSHD), Duchenne muscular dystrophy (DMD), and amyotrophic lateral sclerosis (ALS). RWS and its performance outcome (PerfO) measure RSA have demonstrated strong associations with established clinical measures of disease severity, patient\u2010reported outcomes (PROs), and functional performance, further supporting its clinical relevance. As an UE functional assessment tool, RWS has also shown its generalizable application in various other conditions with UE impairment, such as stroke, orthopedic conditions, and other musculoskeletal disorders. With significant body of work supporting sensor\u2010based RWS as a clinically useful assessment of UE function, future developments incorporating increasingly\u2010capable mobile sensing technologies for remote monitoring and applying machine learning and artificial intelligence (AI) approaches to the sensor\u2010acquired motion data promise further exciting possibilities to enhance clinical studies and patient care.<\/jats:p>","DOI":"10.1002\/mus.70190","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T10:46:36Z","timestamp":1775817996000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Reachable Workspace as a Clinical Outcome for Upper Extremity Function: A Narrative Review"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5618-0942","authenticated-orcid":false,"given":"Jay J.","family":"Han","sequence":"first","affiliation":[{"name":"Department of Physical Medicine &amp; Rehabilitation University of California Irvine School of Medicine  Orange California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence J.","family":"Hayward","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Massachusetts Chan Medical School  Worcester Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Adams","sequence":"additional","affiliation":[{"name":"Fulcrum Therapeutics Inc.  Cambridge Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Perez\u2010Ibarra","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine &amp; Rehabilitation University of California Irvine School of Medicine  Orange California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,10]]},"reference":[{"issue":"1","key":"e_1_2_13_2_1","doi-asserted-by":"crossref","first-page":"7001350010p1","DOI":"10.5014\/ajot.2016.015487","article-title":"Range of Motion Requirements for Upper\u2010Limb Activities of Daily Living","volume":"70","author":"Gates D. 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