{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T03:53:41Z","timestamp":1777953221488,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction\/Aims<\/jats:title>\n                    <jats:p>Identifying factors associated with short\u2010term relapse is essential for tailoring maintenance treatment on a case\u2010by\u2010case basis in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We sought to determine whether changes in demyelinating electrophysiological features during treatment could predict relapse after treatment discontinuation in a cohort of CIDP patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective study of patients with CIDP treated with intravenous immunoglobulin (IVIg), all of whom had a first nerve conduction study (NCS) at treatment initiation or during treatment, while the disease was in a stable phase, followed by a second study at the time of treatment discontinuation. Demyelinating features and the degree of axonal loss were determined during each NCS and compared between the two examinations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty\u2010one consecutive IVIg\u2010responsive CIDP patients were included, with a mean age of 59.1\u2009\u00b1\u200914.6\u2009years. Twenty (65%) were males. Sixteen patients (52%) relapsed after a mean of 6\u2009months. Most patients demonstrated a reduced total number and type of demyelinating features between the two assessments, but overall, these changes were not different between the relapse and relapse\u2010free groups. Similarly, axonal loss at our first assessment and the progression of axonal loss between our two assessments were not different in the relapse group compared to the relapse\u2010free group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>In our population of IVIg responsive CIDP patients, we were unable to demonstrate the predictive value of follow\u2010up nerve conduction studies alone for the risk of relapse. Looking at other biomarkers alone or in combination with NCS is necessary.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.70199","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:09:24Z","timestamp":1772996964000},"page":"984-989","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evolution of Nerve Conduction Demyelinating Parameters Between Baseline and Treatment Cessation May Not Be Predictive of Relapse in\n                    <scp>IVIg<\/scp>\n                    \u2010Responsive\n                    <scp>CIDP<\/scp>\n                    Patients"],"prefix":"10.1002","volume":"73","author":[{"given":"Marine","family":"Le Vavasseur","sequence":"first","affiliation":[{"name":"Service de Physiologie Clinique\u2010Explorations Fonctionnelles, APHP, DMU DREAM, H\u00f4pital Lariboisi\u00e8re  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Capucine","family":"Blaise","sequence":"additional","affiliation":[{"name":"Service de Physiologie Clinique\u2010Explorations Fonctionnelles, APHP, DMU DREAM, H\u00f4pital Lariboisi\u00e8re  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Cordelle","sequence":"additional","affiliation":[{"name":"Service de Neurologie, Groupe Hospitalier Paris Saint Joseph  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauline","family":"Reach","sequence":"additional","affiliation":[{"name":"Service de Neurologie, Groupe Hospitalier Paris Saint Joseph  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahar","family":"Chakroun","sequence":"additional","affiliation":[{"name":"Service de Physiologie Clinique\u2010Explorations Fonctionnelles, APHP, DMU DREAM, H\u00f4pital Lariboisi\u00e8re  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalie","family":"Kubis","sequence":"additional","affiliation":[{"name":"Service de Physiologie Clinique\u2010Explorations Fonctionnelles, APHP, DMU DREAM, H\u00f4pital Lariboisi\u00e8re  Paris France"},{"name":"Universit\u00e9 Paris Cit\u00e9, INSERM UMRS\u20101144  Paris France"},{"name":"Centre de comp\u00e9tence Neuropathies Rares et amylo\u00efdes Ile\u2010de France Cara\u00efbes (CERAMIC) FILNEMUS, AP\u2010HP, H\u00f4pital Lariboisi\u00e8re  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Lozeron","sequence":"additional","affiliation":[{"name":"Service de Physiologie Clinique\u2010Explorations Fonctionnelles, APHP, DMU DREAM, H\u00f4pital Lariboisi\u00e8re  Paris France"},{"name":"Universit\u00e9 Paris Cit\u00e9, INSERM UMRS\u20101144  Paris France"},{"name":"Centre de comp\u00e9tence Neuropathies Rares et amylo\u00efdes Ile\u2010de France Cara\u00efbes (CERAMIC) FILNEMUS, AP\u2010HP, H\u00f4pital Lariboisi\u00e8re  Paris 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