{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T05:50:53Z","timestamp":1781934653550,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["91819613"],"award-info":[{"award-number":["91819613"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction\/Aims<\/jats:title>\n                    <jats:p>Respiratory muscle dysfunction is prevalent in congenital myopathies and often leads to respiratory failure. Ultrasound shear wave elastography (SWE) measures tissue elasticity and has been proposed as an alternative to invasive measures of respiratory muscle contractility. This study aims to evaluate SWE to assess respiratory muscle function in healthy individuals and congenital myopathy patients, while also determining SWE reliability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Shear wave velocity in the diaphragm, parasternal intercostal, sternocleidomastoid, external oblique, internal oblique, and transverse abdominal muscles was acquired in healthy participants and congenital myopathy patients during different maneuvers. Mouth pressure (Pmo) was acquired simultaneously with SWE acquisition. Furthermore, transdiaphragmatic pressure (Pdi) was acquired in healthy participants. All measurements were repeated by two observers to assess reliability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010one congenital myopathy patients and 20 healthy participants were included. Shear wave velocity did not differ between healthy participants and patients during any maneuver in any muscle, and Pmo and Pdi were not correlated with shear wave velocity. Intraobserver intraclass correlation coefficients (ICC) varied between 0.28\u20130.95 for healthy participants and 0.62\u20130.95 for patients. Interobserver ICC varied between 0.00 and 0.87 for healthy participants and 0.00\u20130.79 for patients. Test\u2013retest ICC varied between 0.00\u20130.66 for healthy participants and 0.00\u20130.72 for patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The absence of differences in shear wave velocity between healthy participants and patients, and the low reliability estimates, indicate that SWE of the respiratory muscles is not suitable in routine clinical care or research. The complex mechanical properties of the respiratory muscles introduce challenges that may require alternative SWE techniques.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.70252","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T04:12:21Z","timestamp":1777003941000},"page":"103-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Shear Wave Elastography to Assess Respiratory Muscle Function in Congenital Myopathies"],"prefix":"10.1002","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9374-9875","authenticated-orcid":false,"given":"J. L. M.","family":"van Doorn","sequence":"first","affiliation":[{"name":"Department of Neurology, Clinical Neuromuscular Imaging Group, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0439-6997","authenticated-orcid":false,"given":"D.","family":"Jans","sequence":"additional","affiliation":[{"name":"Department of Neurology, Clinical Neuromuscular Imaging Group, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1987-6948","authenticated-orcid":false,"given":"C. L.","family":"de Korte","sequence":"additional","affiliation":[{"name":"Medical Ultrasound Imaging Centre, Department of Medical Imaging Radboud University Medical Centre  Nijmegen the Netherlands"},{"name":"Physics of Fluids Group, TechMed Centre University of Twente  Enschede the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9867-9047","authenticated-orcid":false,"given":"B. G. M.","family":"van Engelen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5837-7295","authenticated-orcid":false,"given":"N. C.","family":"Voermans","sequence":"additional","affiliation":[{"name":"Department of Neurology, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7839-8125","authenticated-orcid":false,"given":"N.","family":"van Alfen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Clinical Neuromuscular Imaging Group, Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8808-4813","authenticated-orcid":false,"given":"C. A. C.","family":"Ottenheijm","sequence":"additional","affiliation":[{"name":"Department of Physiology Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6335-9916","authenticated-orcid":false,"given":"D.","family":"Bachasson","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, INSERM, UMRS1158 Neurophysiologie Respiratoire Exp\u00e9rimentale et Clinique  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4157-1649","authenticated-orcid":false,"given":"J.","family":"Doorduin","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2206020"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2022.102328"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01214-2018"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1007236"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00137-2021"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23702"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-015-3687-3"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000004042"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2016-209459"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00095.2017"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000541632"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2018.03.009"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2013.01.022"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01060.2018"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2013.11.003"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.27639"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00080312"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2018.08.37"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.2.420"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcm.2016.02.012"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-017-0419-z"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2017.191"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/11795972241294115"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2023.111553"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1109\/TUFFC.2004.1295425"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2010.02.013"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/17434440.2018.1538782"}],"container-title":["Muscle &amp; 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