{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T23:13:46Z","timestamp":1771629226692,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":9782,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1978,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Several studies have suggested that muscle lactic acid production is defective in alcoholic myopathy. However, normal controls have not been evaluated. To study the effects of ethanol on the production of lactic acid in normal exercised muscle, oral ethanol (1 g per kg body weight, 20% v\/v) was given to eight nonalcoholic subjects. Forearm ischemic exercise with a total work load of 7.2 kg\u2010m\/min was performed just before and 90 min after ingestion of ethanol. At the time of exercise, the serum ethanol level was 95.7 \u00b1 15.1 mg% (mean \u00b1 SD). Resting serum lactic acid was significantly higher after ingestion of ethanol (15.7 \u00b1 4.5 mg%) than before (8.5 \u00b1 4.7 mg%). Lactic acid generation with ischemic exercise was significantly lower after ethanol ingestion. The mean peak serum lactic acid level (expressed as percentage elevation above resting) was 330.5 \u00b1 118.2% before and 127.9 \u00b1 75.1% after (p &lt;.05). These results indicate that a single oral dose of ethanol decreases lactic acid production by exercised muscle in normal subjects.<\/jats:p>","DOI":"10.1002\/mus.880010108","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T07:49:33Z","timestamp":1104565773000},"page":"57-61","source":"Crossref","is-referenced-by-count":13,"title":["Effect of ethanol on lactic acid production by exercised normal muscle"],"prefix":"10.1002","volume":"1","author":[{"given":"Luis A.","family":"Chui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodore L.","family":"Munsat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"Craig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"105","article-title":"Acute antilipolytic effect of ethyl alcohol and acetate in man","volume":"72","author":"Abramson BA","year":"1968","journal-title":"J Lab Clin Med"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-6525-3_6"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.25.5.405"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0022-2275(20)42731-2","article-title":"Role of acetate in the reduction of plasma free fatty acids produced by ethanol in man","volume":"9","author":"Crouse JR","year":"1968","journal-title":"J Lipid Res"},{"key":"e_1_2_1_6_2","first-page":"19","article-title":"Alcoholic myopathy","volume":"33","author":"Curran RJ","year":"1972","journal-title":"Dis Nerv Sys"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1152\/ajplegacy.1975.229.2.255","article-title":"Uptake of lactate by dog skeletal muscle in vivo and the effect of free fatty acids","volume":"229","author":"Dunn RB","year":"1975","journal-title":"Am J Physiol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1152\/jappl.1975.38.5.801","article-title":"Effect of circulating FFA on lactate production by skeletal muscle during stimulation","volume":"28","author":"Dunn RB","year":"1975","journal-title":"J Appl Physiol"},{"key":"e_1_2_1_9_2","unstructured":"Ethanol Assay Enzymatic Analysis by Sigma Technical. 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