{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:55:41Z","timestamp":1759694141965},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":9478,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1978,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Twenty\u2010seven patients (18 females and 9 males) with myasthenia gravis were HLA\u2010A, \u2010B, \u2010C, and \u2010D typed, and the results were analyzed with relation to evidence of immunodeficiency, thymic disease, and associated autoimmune processes. An association of A1, B8, and DRW3 appeared to identify a group of 8 females with higher mean anti\u2010DNA, lower mean C4, and lower mean <jats:italic>E. coli<\/jats:italic> antibody titer than other females in whom CW4 (with or without BW35) was common (6 of the remaining 10 females were in this category). Antiacetylcholine receptor (anti\u2010AChR) autoantibody and reduced serum lgM and isohemagglutinin titers were not clearly related to particular HLA specificities. These results suggest that HLA\u2010A1, \u2010B8, \u2010DRW3, and \u2010CW4 may be related to associated phenomena rather than playing a major role in the development of anti\u2010AChR and myasthenia gravis.<\/jats:p>","DOI":"10.1002\/mus.880010605","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T07:51:37Z","timestamp":1104565897000},"page":"467-470","source":"Crossref","is-referenced-by-count":18,"title":["HLA, anti\u2010DNA, and complement in myasthenia gravis"],"prefix":"10.1002","volume":"1","author":[{"given":"Frank T.","family":"Christiansen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Houliston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger L.","family":"Dawkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1976.tb47707.x"},{"key":"e_1_2_1_3_2","first-page":"133","volume-title":"The Australasian Tissue Typing Workshop","author":"Dawkins RL","year":"1977"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5899.131"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1976.tb47705.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000231597"},{"key":"e_1_2_1_7_2","first-page":"48","article-title":"Studies on HLA antigens and cellular and humoral autoimmune phenomena in patients with myasthenia gravis","volume":"27","author":"Gross WL","year":"1977","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_8_2","first-page":"100","volume-title":"The Australasian Tissue Typing Workshop","author":"Hawkins BR","year":"1977"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(77)90027-7"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90153-X"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.1976.tb01027.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1976.tb47708.x"},{"key":"e_1_2_1_13_2","first-page":"66","article-title":"The reactivity of the antistriational antibodies associated with thymoma and myasthenia gravis","volume":"27","author":"Peers J","year":"1977","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1976.tb47706.x"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.28.020177.002233"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5922.16"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880010605","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880010605","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T11:20:34Z","timestamp":1699788034000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880010605"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,11]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1978,11]]}},"alternative-id":["10.1002\/mus.880010605"],"URL":"https:\/\/doi.org\/10.1002\/mus.880010605","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,11]]}}}