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Morphologic evidence of a mild distal axonal neuropathy in the ventral caudal nerve was produced. The red blood cell transketolase levels were normal, indicating that the rats were not deficient in thiamine and suggesting that the axonal degeneration was due to the direct toxic effect of alcohol. Axonal transport studies demonstrated a significant increase in the amount of acetylcholinesterase transported in an orthograde direction in the sciatic nerves of alcohol\u2010exposed rats, and indicated no change in the transport of choline acetyltransferase or in the specific binding of colchicine by neurotubulin.<\/jats:p>","DOI":"10.1002\/mus.880020208","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T07:54:10Z","timestamp":1104566050000},"page":"133-144","source":"Crossref","is-referenced-by-count":71,"title":["Animal models of alcoholic neuropathy: Morphologic, electrophysiologic, and biochemical findings"],"prefix":"10.1002","volume":"2","author":[{"given":"E. P.","family":"Bosch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. W.","family":"Pelham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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