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We review evidence from research in neuromuscular, neurological, and other genetic diseases of humans that suggests the contrary. There are now examples of single clinical syndromes related to each of several defects, of defects of one biochemical reaction related to two or more distinct clinical syndromes, and of partial defects associated with disease in a way that suggests a causal relationship.<\/jats:p>","DOI":"10.1002\/mus.880040107","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T07:57:37Z","timestamp":1104566257000},"page":"31-40","source":"Crossref","is-referenced-by-count":6,"title":["Multiple genotypes, multiple phenotypes, and partial defects"],"prefix":"10.1002","volume":"4","author":[{"given":"R. A. 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