{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T09:18:50Z","timestamp":1726391930972},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":7591,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1984,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report two female patients with a history of alcohol abuse presenting with proximal painful muscle weakness following aversion therapy with emetine hydrochloride. Muscle biopsy of Case 1 showed a reversible floccular\u2010shaped loss of myosin ATPase and dehydrogenase, and accumulation of PAS positive material, and a normal lipid content. Repeat biopsy showed core change with no focal loss of myosin ATPase. In Case 2, muscle biopsy was taken 1 month after commencement of emetine therapy and revealed similar but milder changes to Case 1. Electron microscopy revealed Z\u2010band streaming with a decrease or loss of mitochondria. Sarcotubular systems appeared normal in shape and size. Anaerobic glycolysis on homogenate from the initial biopsy of Case 1 showed generalized reduction of lactate formation, which returned to normal in the repeat biopsy.<\/jats:p>","DOI":"10.1002\/mus.880070109","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T04:41:55Z","timestamp":1104554515000},"page":"54-59","source":"Crossref","is-referenced-by-count":27,"title":["Emetine myopathy: Two case reports with pathobiochemical analysis"],"prefix":"10.1002","volume":"7","author":[{"given":"H.","family":"Sugie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Russin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Anthony","family":"Verity","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.22.4.501"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.32.1.91"},{"key":"e_1_2_1_4_2","first-page":"266","volume-title":"Method of Enzymatic Analysis","author":"Bergmeyer HU","year":"1963"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(78)90183-1"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1976.tb07653.x"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.21.6.579"},{"key":"e_1_2_1_8_2","first-page":"12","volume-title":"Third International Congress on Muscle Diseases","author":"Currie S","year":"1974"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.20.8.733"},{"key":"e_1_2_1_10_2","first-page":"253","volume-title":"Muscle Biopsy: A Modern Approach","author":"Dubowitz V","year":"1973"},{"key":"e_1_2_1_11_2","first-page":"73","volume-title":"Current Topics in Nerve and Muscle Research","author":"Ebashi S","year":"1979"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1964.00460170019003"},{"key":"e_1_2_1_13_2","first-page":"666","article-title":"Multicore disease: a recently recognized congential myopathy associated with multifocal degeneration of muscle fibers","volume":"46","author":"Engel AG","year":"1971","journal-title":"Proc Mayo Clin"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/191389a0"},{"key":"e_1_2_1_15_2","first-page":"594","volume-title":"Clinical Studies in Myology","author":"Fewings JD","year":"1971"},{"key":"e_1_2_1_16_2","first-page":"1074","volume-title":"The Pharmacological Basis of Therapeutics","author":"Goodman LS","year":"1975"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(80)90204-X"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1972.00490150045008"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-28-5-892"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880030302"},{"key":"e_1_2_1_21_2","first-page":"122","article-title":"Mitochondrial protein synthesis: inhibition by emetine hydrochloride","volume":"7","author":"Lietman PS","year":"1971","journal-title":"Mol Pharmacol"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)52451-6"},{"key":"e_1_2_1_23_2","first-page":"5960","article-title":"Reversible ipecac myopathy","volume":"29","author":"Mateer J","year":"1979","journal-title":"Neurology (Minneap)"},{"key":"e_1_2_1_24_2","first-page":"8","article-title":"Selective damage of myocardial mitochondria due to emetine hydrochloride","volume":"91","author":"Pearce MB","year":"1971","journal-title":"Arch Pathol"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.22.020171.001013"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1159\/000114311"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI103983"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/79.4.610"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2828(78)90042-1"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880070109","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880070109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T02:30:29Z","timestamp":1697769029000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880070109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,1]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1984,1]]}},"alternative-id":["10.1002\/mus.880070109"],"URL":"https:\/\/doi.org\/10.1002\/mus.880070109","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,1]]}}}