{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T23:27:33Z","timestamp":1773271653735,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":7409,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1984,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The effects of thyrotoxicosis on the contractile properties and development of muscle fatigue in the slow soleus (SOL) and fast extensor digitorum longus (EDL) muscles were examined in rats given 3 mg of L\u2010thyroxine and 1 mg of L\u2010triiodothyronine per kilogram of diet for 6 weeks. The hormone treatment produced significant decreases in the contraction time, one\u2010half relaxation time, and twitch tension in the SOL, while the peak rate of tension development (+ dP\/dt) and decline (\u2212 dP\/dt) in this muscle were elevated. Additionally, the forcefrequency curve was shifted to the right and, thus, resembled the curve of a normal fast\u2010twitch muscle. In contrast, the contractile properties of the fast EDL were relatively unaltered by the hormone administration. Thyrotoxicosis also changed the SOL response to contractile activity as twitch tension, + dP\/dt, and \u2212 dP\/dt remained high, and a faster decline in muscle glycogen and an increase in lactate occurred compared to control muscles. These results clearly demonstrate a preferential effect of thyroid hormone on slow compared to fast skeletal muscle.<\/jats:p>","DOI":"10.1002\/mus.880070609","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T04:47:51Z","timestamp":1104554871000},"page":"470-477","source":"Crossref","is-referenced-by-count":24,"title":["Contractile and fatigue properties of thyrotoxic rat skeletal muscle"],"prefix":"10.1002","volume":"7","author":[{"given":"Robert H.","family":"Fitts","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl J.","family":"Brimmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P.","family":"Troup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian R.","family":"Unsworth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1980.sp013137"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1980.238.1.C15"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106298"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.26.2.555"},{"key":"e_1_2_1_6_2","first-page":"35","article-title":"Chemical procedures for analysis of polysaccharides","volume":"3","author":"Hassid WZ","year":"1957","journal-title":"Methods Enzymol"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1938.0050"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-395630-9.50058-X"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.38.030176.001421"},{"key":"e_1_2_1_10_2","first-page":"593","volume-title":"Plasticity of Muscle","author":"Ianuzzo CD","year":"1980"},{"key":"e_1_2_1_11_2","first-page":"465","volume-title":"Harrison's Principles of International Medicine","author":"Ingbar SH","year":"1974"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1982.243.3.C151"},{"key":"e_1_2_1_13_2","first-page":"615","article-title":"Abh\u00e4ngigkeit der aktivit\u00e4t liniger enzyme des glykogenstoffwechsels des skeletmuskels der ratte vom schilddr\u00fcsenstatus","volume":"21","author":"Krause EG","year":"1968","journal-title":"Acta Biol Med Ger"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1971.tb01276.x"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-091304-6.50028-8"},{"key":"e_1_2_1_16_2","first-page":"246","volume-title":"Biochemistry, A Functional Approach","author":"McGilvery RW","year":"1970"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00582715"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00713269"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj0860408"},{"key":"e_1_2_1_20_2","first-page":"437","article-title":"Assays of intermediates of the citric acid cycle and related compounds by fluorometric enzyme methods","volume":"13","author":"Williamson JR","year":"1969","journal-title":"Methods Enzymol"},{"key":"e_1_2_1_21_2","first-page":"581","volume-title":"Plasticity of Muscle","author":"Winder WW","year":"1980"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1977.232.5.C180"},{"key":"e_1_2_1_23_2","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1152\/jappl.1983.54.5.1242","article-title":"Effect of hindlimb immobilization on the fatigability of skeletal muscle","volume":"54","author":"Witzmann FA","year":"1983","journal-title":"J Appl Physiol"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880070609","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880070609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T05:26:39Z","timestamp":1697779599000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880070609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,7]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1984,7]]}},"alternative-id":["10.1002\/mus.880070609"],"URL":"https:\/\/doi.org\/10.1002\/mus.880070609","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,7]]}}}