{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T17:45:10Z","timestamp":1759340710471},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":7347,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1984,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A new phosphoglycerate kinase variant (PGK New Jersey) has been purified from muscle and cultured fibroblasts of a patient with recurrent myoglobinuria. The mutant enzyme had higher than normal affinity for adenosine triphosphate (ATP) and 3\u2010phosphoglycerate, and a shift of the pH optimum towards the acidic side. Antibodies raised against PGK purified from normal muscle were used to evaluate the presence of immunologically cross\u2010reacting enzyme protein in tissues from the patient. Immunodiffusion and an antibody consumption test showed the presence of reduced amounts of cross\u2010reacting material in the patient's muscle. Several PGK variants have been characterized in asymptomatic individuals or in patients with hemolytic anemia. The biochemical features of PGK New Jersey, the only known variant associated with recurrent myoglobinuria, distinguish this mutant enzyme from others.<\/jats:p>","DOI":"10.1002\/mus.880070705","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T04:27:40Z","timestamp":1104553660000},"page":"542-551","source":"Crossref","is-referenced-by-count":13,"title":["Phosphoglycerate kinase deficiency myopathy: Biochemical and immunological studies of the mutant enzyme"],"prefix":"10.1002","volume":"7","author":[{"given":"Nereo","family":"Bresolin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armand","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai Won","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Shanske","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"DiMauro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1973.tb00333.x"},{"key":"e_1_2_1_3_2","first-page":"495","article-title":"Deficit en 3\u2010phosphoglycerate kinase erythrocytaire et leukocytaire","volume":"14","author":"Boivin P","year":"1974","journal-title":"Nouv Rev Fr Hematol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1974.tb03557.x"},{"key":"e_1_2_1_5_2","first-page":"565","article-title":"Anemie hemolytique congenitale associee a un deficit en phosphoglycerate kinase dans les globules rouges, les polynucleaires et les lymphocytes","volume":"11","author":"Cartier P","year":"1971","journal-title":"Nouv Rev Fr Hematol"},{"key":"e_1_2_1_6_2","first-page":"229","article-title":"Phosphoglycerate kinase: additional variants and their geographic distribution","volume":"24","author":"Chen SH","year":"1972","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_7_2","first-page":"87","article-title":"Phosphoglycerate kinase: an X\u2010linked polymorphism in man","volume":"23","author":"Chen SH","year":"1971","journal-title":"Am J Hum Genet"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.175.4025.1002"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410130104"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(71)80236-X"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00789a030"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.4.2587"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"6421","DOI":"10.1016\/S0021-9258(18)43755-6","article-title":"A single amino acid substitution (Asp Asn) in a phosphoglycerate kinase variant (PGK Munchen) associated with enzyme deficiency","volume":"25","author":"Fujii H","year":"1980","journal-title":"J Biol Chem"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4838(82)90179-0"},{"key":"e_1_2_1_15_2","unstructured":"HjelmM WadmanB:Non spherocytic haemolytic anemia with phosphoglycerate kinse deficiency. 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