{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T06:52:16Z","timestamp":1761807136321},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":6952,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1985,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Forty\u2010three patients with myotonic dystrophy (MyD) and 43 age\u2010 and sex\u2010matched controls were prospectively evaluated for mitral valve prolapse (MVP) using both cardiac auscultation and echocardiography (ECHO). Prevalence of MVP was significantly increased in MyD patients when using either abnormal auscultation plus abnormal ECHO (23.3%, <jats:italic>P<\/jats:italic> &lt; 0.02) or abnormal ECHO alone (30%, <jats:italic>P<\/jats:italic> &lt; 0.01) as diagnostic criteria for MVP. Frequency of MVP was even more increased in patients with a thin, flat chest compared with patients with normal physical appearance (<jats:italic>P<\/jats:italic> &lt; 0.007). These findings are in support of the concept that the increased frequency of MVP in neuromuscular disorders is likely due to geometrical changes of the heart caused by thorax deformities, rather than structural changes of the mitral valve. For this reason, MVP in MyD probably belongs to the entity of so\u2010called benign, secondary MVP. This is further supported by the absence of symptoms of \u201csystemic\u201d complications of MVP in our patient population.<\/jats:p>","DOI":"10.1002\/mus.880080804","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T08:48:43Z","timestamp":1104569323000},"page":"650-653","source":"Crossref","is-referenced-by-count":13,"title":["Mitral valve prolapse in myotonic dystrophy"],"prefix":"10.1002","volume":"8","author":[{"given":"Erich W.","family":"Streib","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David G.","family":"Meyers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sallie F.","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1976.00500110045008"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(75)90863-2"},{"key":"e_1_2_1_4_2","first-page":"130","article-title":"Dystrophia myotonia with heart block: a light and electron microscopic study","volume":"84","author":"Bullock RT","year":"1967","journal-title":"Arch Pathol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198209233071302"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)90113-7"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90235-2"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(77)90648-9"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-97-6-826"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(82)90644-5"},{"key":"e_1_2_1_11_2","volume-title":"Myotonic Dystrophy","author":"Harper PS","year":"1979"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1001\/archinte.1983.00350110120025","article-title":"Families with myotonic dystrophy with and without cardiac involvement","volume":"143","author":"Hawley RJ","year":"1983","journal-title":"Arch Intern Med"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000169913"},{"key":"e_1_2_1_14_2","first-page":"4","volume-title":"Mitral Valve Prolapse","author":"Jeresaty RM","year":"1979"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.115.1.179"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(78)90207-7"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.38.3.244"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.53.3.464"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197707072970103"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.13.1.93"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(79)90795-2"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1980.00500540051004"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.35.3.245"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(75)90864-4"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.62.2.430"},{"key":"e_1_2_1_26_2","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1542\/peds.63.1.116","article-title":"Mitral valve prolapse syndrome in children with Duchenne's progressive muscular dystrophy","volume":"63","author":"Sanyal SK","year":"1979","journal-title":"Pediatrics"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(77)90003-0"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.63.3.559"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-85-1-19"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960070403"}],"container-title":["Muscle &amp; 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