{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:14:25Z","timestamp":1760188465027},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":5644,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1989,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We have carried out a comparative study of caffeine sensitivity of the sarcoplasmic reticulum (SR) of fast and slow normal human fibers chemically skinned. Human slow\u2010fiber SR is more sensitive to caffeine than fast fiber SR; however, it releases less calcium and at a lower rate than the SR of fast fibers when exposed to threshold concentrations of caffeine. These results indicate that the SR calcium release mechanisms of SR of fast and slow human fibers are homologous but not identical. An increased sensitivity of SR to caffeine is found in both fast and slow fibers from human malignant hyperthermia muscle. However, fast fibers seem to be the most affected, since their caffeine threshold for contraction is very close to that of slow fibers.<\/jats:p>","DOI":"10.1002\/mus.880120505","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T05:14:16Z","timestamp":1104556456000},"page":"365-370","source":"Crossref","is-referenced-by-count":12,"title":["Caffeine sensitivity of sarcoplasmic reticulum of fast and slow fibers from normal and malignant hyperthermia human muscle"],"prefix":"10.1002","volume":"12","author":[{"given":"Giovanni","family":"Salviati","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romeo","family":"Betto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Ceoldo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Tegazzin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Della","family":"Puppa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1970.sp009158"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1042\/bj2500307","article-title":"Myosin heavy chain composition of single fibres from normal human muscle","volume":"250","author":"Biral D","year":"1988","journal-title":"Biochem J"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03007740"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03007119"},{"key":"e_1_2_1_6_2","first-page":"349","article-title":"Twitch potentiation and caffeine contractures in isolated rat soleus muscle","volume":"74","author":"Connett RJ","year":"1983","journal-title":"Comp Biochem Physiol"},{"key":"e_1_2_1_7_2","first-page":"521","article-title":"In vitro response of cat skeletal muscle to halothane and caffeine","volume":"58","author":"Deuster PA","year":"1985","journal-title":"Am J Physiol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1985.sp015541"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.80.2.279"},{"key":"e_1_2_1_10_2","first-page":"404","article-title":"Caffeine\u2010induced contracture in mammalian skeletal muscle","volume":"15","author":"Gutman E","year":"1966","journal-title":"Physiol Bohemoslov"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198707000-00014"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1981.sp013857"},{"key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1152\/ajplegacy.1970.218.1.33","article-title":"Contracture and twitch potentiation of fast and slow muscle of the rat at 20 C and 30 C","volume":"218","author":"Isaacson AM","year":"1970","journal-title":"Am J Physiol"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(73)90023-3"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1984.64.4.1240"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03007997"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1988.tb02699.x"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1977.233.5.C127"},{"key":"e_1_2_1_19_2","doi-asserted-by":"crossref","first-page":"6135","DOI":"10.1016\/S0021-9258(18)45548-2","article-title":"Drug\u2010induced calcium release from isolated sarcoplasmic reticulum","volume":"262","author":"Palade P","year":"1987","journal-title":"J Biol Chem"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00640912"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.79.4.603"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1988.254.3.C459"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.88.5.573"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1981.sp013825"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880060707"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.87.2.289"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.52.5.750"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(78)90135-8"},{"key":"e_1_2_1_29_2","first-page":"597","volume-title":"Disorders of the Motor Unit","author":"Wood DS","year":"1982"},{"key":"e_1_2_1_30_2","doi-asserted-by":"crossref","first-page":"7349","DOI":"10.1016\/S0021-9258(17)39615-1","article-title":"Doxorubicin induces calcium release from terminal cisternae of skeletal msucle","volume":"260","author":"Zorzato F","year":"1985","journal-title":"J Biol Chem"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880120505","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880120505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T05:12:50Z","timestamp":1697951570000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880120505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,5]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1989,5]]}},"alternative-id":["10.1002\/mus.880120505"],"URL":"https:\/\/doi.org\/10.1002\/mus.880120505","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,5]]}}}