{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:28:08Z","timestamp":1761596888523},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":5309,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1990,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 22\u2010year\u2010old male was studied 3\u00bd\u2013&amp;4\u00bd years after a traumatic section\u2010avulsion amputation of the left upper extremity at the level of the distal humerus. The arm was reattached after a cold ischemia time of 4\u20135 hours and good vascularization was obtained. The ulnar nerve was repaired early with an end\u2010to\u2010end juncture while the median and radial nerves were repaired after seven months delay using a combination of vascularized radial nerve and nonvascularized sural nerve grafts. Some intrinsic hand muscle function had recovered. Pin\u2010prick and touch sensation was present in all digits, although localization of touch stimulation was poor. Evoked motor responses had recovered by 25\u201350% of control amplitude in ulnar\u2010innervated and by 10\u201325% in median\u2010innervated muscles. Amplitudes of sensory responses from digit V had recovered by 25% and from digits I and III by 1\u20135%. Fast\u2010adapting touch receptors had become reinnervated. There was electrophysiological evidence of aberrant sensory regeneration and of abnormal connections between sensory and motor fibers. Digital blood flow measurements suggested the presence of vascular obstruction in vessels of the replanted upper extremity. However, the digital vasconstriction during cold exposure indicated regeneration of sympathetic nerve fibers.<\/jats:p>","DOI":"10.1002\/mus.880130404","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T09:37:19Z","timestamp":1104572239000},"page":"291-304","source":"Crossref","is-referenced-by-count":28,"title":["Nerve regeneration and reinnervation after limb amputation and replantation: Clinical and physiological findings"],"prefix":"10.1002","volume":"13","author":[{"given":"Christian","family":"Krarup","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Upton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A.","family":"Creager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.08-03-01026.1988"},{"key":"e_1_2_1_3_2","first-page":"166","article-title":"Preferential motor reinnervation: a sequential double labeling study","volume":"14","author":"Brushart TME","year":"1988","journal-title":"Neurosci Abstr"},{"key":"e_1_2_1_4_2","first-page":"5","article-title":"Human nerve potentials evoked by tactile stimuli. 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