{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T10:14:14Z","timestamp":1698142454582},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,10,13]],"date-time":"2004-10-13T00:00:00Z","timestamp":1097625600000},"content-version":"vor","delay-in-days":4975,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[1991,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A clonal human skeletal muscle cell line showing acid maltase deficiency (AMD) was established through the transfection of origin\u2010defective SV40 DNA. The low acid \u03b1\u2010glucosidase activity and glycogenosomes in this clone corresponded to AMD. This clone, in spite of loading glycogenosomes, was competent not only as to proliferation without contact inhibition but also as to myogenic differentiation to some extent. Dexamethasone promoted the formation by the transformant of multinucleated myotubes, which expressed acetylcholine receptors. The existence of glycogenosomes did not seem to affect the proliferation or differentiation of myoblasts. The aberrant acid \u03b1\u2010glucosidase expressed in the transformed myogenic clone was shown to be biochemically identical to that in AMD fibroblasts. This transformant should be of great value for investigating the pathogenesis of AMD because of the possibility of supplying semi\u2010permanently a uniform myogenic cell line expressing AMD.<\/jats:p>","DOI":"10.1002\/mus.880140308","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T10:31:34Z","timestamp":1104575494000},"page":"245-252","source":"Crossref","is-referenced-by-count":0,"title":["Human acid maltase\u2010deficient myogenic cell transformation with origin\u2010defective SV40: Characterization of a cloned line"],"prefix":"10.1002","volume":"14","author":[{"given":"Fusako","family":"Usuki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itsuro","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuko","family":"Soejima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakazu","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikuro","family":"Maruyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiro","family":"Osame","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,13]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.3.1409"},{"key":"e_1_2_1_3_2","series-title":"Excerpta Media International Congress Series No. 199","first-page":"236","volume-title":"Muscle Dis Int Proc Internat Congr","author":"Engel AG","year":"1969"},{"key":"e_1_2_1_4_2","first-page":"285","volume-title":"Muscle Regeneration","author":"Engel WK","year":"1979"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/jss.400070305"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01819299"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1980.044.01.033"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.77.7.3898"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj0860011"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410200504"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01116890"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.140.3573.1273"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2007.00901.x"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)52451-6"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1984.04050130053022"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.27.2.178"},{"key":"e_1_2_1_17_2","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1242\/jcs.89.4.481","article-title":"Characterization of mutant human fibroblast cultures transformed with simian virus 40","volume":"89","author":"Miranda AF","year":"1988","journal-title":"J Cell Sci"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(88)90077-9"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410250614"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/296671a0"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880110413"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.880140308","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.880140308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T09:34:43Z","timestamp":1698053683000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.880140308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,3]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1991,3]]}},"alternative-id":["10.1002\/mus.880140308"],"URL":"https:\/\/doi.org\/10.1002\/mus.880140308","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,3]]}}}